Detalhe da pesquisa
1.
The STAT3-MYC axis promotes survival of leukemia stem cells by regulating SLC1A5 and oxidative phosphorylation.
Blood;
139(4): 584-596, 2022 01 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34525179
2.
The Lateral Metalation of Isoxazolo[3,4-d]pyridazinones towards Hit-to-Lead Development of Selective Positive Modulators of Metabotropic Glutamate Receptors.
Molecules;
28(19)2023 Sep 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37836643
3.
10-Alkoxy-anthracenyl-isoxazole analogs have sub-micromolar activity against a Glioblastoma multiforme cell line.
Bioorg Med Chem;
69: 116911, 2022 09 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35792402
4.
Inhibition of BRAF and ERK1/2 has synergistic effects on thyroid cancer growth in vitro and in vivo.
Mol Carcinog;
60(3): 201-212, 2021 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33595872
5.
N-Substituted pyrrolopyrimidines and purines as p90 ribosomal S6 protein kinase-2 (RSK2) inhibitors.
Bioorg Med Chem;
41: 116220, 2021 07 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34034149
6.
Substituted pteridinones as p90 ribosomal S6 protein kinase (RSK) inhibitors: A structure-activity study.
Bioorg Med Chem;
28(5): 115303, 2020 03 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31982240
7.
10-N-heterocylic aryl-isoxazole-amides (AIMs) have robust anti-tumor activity against breast and brain cancer cell lines and useful fluorescence properties.
Bioorg Med Chem;
28(22): 115781, 2020 11 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33038788
8.
Genetic Variants of Lipoprotein Lipase and Regulatory Factors Associated with Alzheimer's Disease Risk.
Int J Mol Sci;
21(21)2020 Nov 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33172164
9.
Isoxazolo[3,4-d]pyridazinones positively modulate the metabotropic glutamate subtypes 2 and 4.
Bioorg Med Chem;
26(17): 4797-4803, 2018 09 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30143366
10.
Dimeric isoxazolyl-1,4-dihydropyridines have enhanced binding at the multi-drug resistance transporter.
Bioorg Med Chem;
25(12): 3223-3234, 2017 06 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28434782
11.
Allosteric inhibitors of the Eya2 phosphatase are selective and inhibit Eya2-mediated cell migration.
J Biol Chem;
289(23): 16349-61, 2014 Jun 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24755226
12.
RSK3: A regulator of pathological cardiac remodeling.
IUBMB Life;
67(5): 331-7, 2015 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25988524
13.
Human ALDH1B1 polymorphisms may affect the metabolism of acetaldehyde and all-trans retinaldehyde--in vitro studies and computational modeling.
Pharm Res;
32(5): 1648-62, 2015 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25413692
14.
AIMing towards improved antitumor efficacy.
Bioorg Med Chem Lett;
25(8): 1765-1770, 2015 Apr 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25782743
15.
Integrated genomic analysis identifies the mitotic checkpoint kinase WEE1 as a novel therapeutic target in medulloblastoma.
Mol Cancer;
13: 72, 2014 Mar 24.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24661910
16.
Neuroprotective Efficacy of the Glucocorticoid Receptor Modulator PT150 in the Rotenone Mouse Model of Parkinson's Disease.
bioRxiv;
2024 Apr 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38659796
17.
The Giardia lamblia ribosome structure reveals divergence in several biological pathways and the mode of emetine function.
Structure;
32(4): 400-410.e4, 2024 Apr 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38242118
18.
Post-translational oxidative modification and inactivation of mitochondrial complex I in epileptogenesis.
J Neurosci;
32(33): 11250-8, 2012 Aug 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22895709
19.
Identification of functionally relevant lysine residues that modulate human farnesoid X receptor activation.
Mol Pharmacol;
83(5): 1078-86, 2013 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23462506
20.
Glycation of glutamate cysteine ligase by 2-deoxy-d-ribose and its potential impact on chemoresistance in glioblastoma.
Neurochem Res;
38(9): 1838-49, 2013 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23743623