Detalhe da pesquisa
1.
Author Correction: 'Stealth' corporate innovation: an emerging threat for therapeutic drug development.
Nat Immunol;
20(11): 1556, 2019 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31605100
2.
Novel mechanisms and functions of complement.
Nat Immunol;
18(12): 1288-1298, 2017 Nov 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29144501
3.
'Stealth' corporate innovation: an emerging threat for therapeutic drug development.
Nat Immunol;
20(11): 1409-1413, 2019 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31562490
4.
Humanization of SLCO2B1 in Rats Increases rCYP3A1 Protein Expression but Not the Metabolism of Erlotinib to OSI-420.
J Pharmacol Exp Ther;
389(1): 87-95, 2024 Mar 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38448247
5.
C1q binding to surface-bound IgG is stabilized by C1r2s2 proteases.
Proc Natl Acad Sci U S A;
118(26)2021 06 29.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34155115
6.
Complement-targeted therapeutics: An emerging field enabled by academic drug discovery.
Am J Hematol;
98 Suppl 4: S82-S89, 2023 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36755352
7.
Tetra- and Hexavalent Siglec-8 Ligands Modulate Immune Cell Activation.
Angew Chem Int Ed Engl;
62(52): e202314280, 2023 Dec 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37947772
8.
From discovery to approval: A brief history of the compstatin family of complement C3 inhibitors.
Clin Immunol;
235: 108785, 2022 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34147650
9.
Complement: a key system for immune surveillance and homeostasis.
Nat Immunol;
11(9): 785-97, 2010 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20720586
10.
Structure of complement fragment C3b-factor H and implications for host protection by complement regulators.
Nat Immunol;
10(7): 728-33, 2009 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19503104
11.
Structural and functional implications of the alternative complement pathway C3 convertase stabilized by a staphylococcal inhibitor.
Nat Immunol;
10(7): 721-7, 2009 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19503103
12.
Therapeutic Peptides as Emerging Options to Restore Misguided Host Defence and Homeostasis: From Teaching to Concept to Clinic.
Chimia (Aarau);
75(6): 495-499, 2021 Jun 30.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34233811
13.
Prolonged intraocular residence and retinal tissue distribution of a fourth-generation compstatin-based C3 inhibitor in non-human primates.
Clin Immunol;
214: 108391, 2020 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32229292
14.
Regulators of complement activity mediate inhibitory mechanisms through a common C3b-binding mode.
EMBO J;
35(10): 1133-49, 2016 05 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27013439
15.
Complement C3-Targeted Therapy: Replacing Long-Held Assertions with Evidence-Based Discovery.
Trends Immunol;
38(6): 383-394, 2017 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28416449
16.
New milestones ahead in complement-targeted therapy.
Semin Immunol;
28(3): 208-22, 2016 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27321574
17.
Complement inhibition in pre-clinical models of periodontitis and prospects for clinical application.
Semin Immunol;
28(3): 285-91, 2016 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27021500
18.
Complement-activation fragment C4a mediates effector functions by binding as untethered agonist to protease-activated receptors 1 and 4.
Proc Natl Acad Sci U S A;
114(41): 10948-10953, 2017 10 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28973891
19.
Protection of host cells by complement regulators.
Immunol Rev;
274(1): 152-171, 2016 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27782321
20.
Complement component C3 - The "Swiss Army Knife" of innate immunity and host defense.
Immunol Rev;
274(1): 33-58, 2016 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27782325