Detalhe da pesquisa
1.
Oncogenic role and target properties of the lysine-specific demethylase KDM1A in chronic lymphocytic leukemia.
Blood;
142(1): 44-61, 2023 07 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37023372
2.
Characterization of structural, biochemical, pharmacokinetic, and pharmacodynamic properties of the LSD1 inhibitor bomedemstat in preclinical models.
Prostate;
84(10): 909-921, 2024 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38619005
3.
LSD1 inhibition exerts its antileukemic effect by recommissioning PU.1- and C/EBPα-dependent enhancers in AML.
Blood;
131(15): 1730-1742, 2018 04 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29453291
4.
A public resource facilitating clinical use of genomes.
Proc Natl Acad Sci U S A;
109(30): 11920-7, 2012 Jul 24.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22797899
5.
Chemical modulation of Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes.
Wellcome Open Res;
8: 146, 2023.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37520936
6.
Inhibition of LSD1 with Bomedemstat Sensitizes Small Cell Lung Cancer to Immune Checkpoint Blockade and T-Cell Killing.
Clin Cancer Res;
28(20): 4551-4564, 2022 10 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35920742
7.
Leukemia Cell of Origin Influences Apoptotic Priming and Sensitivity to LSD1 Inhibition.
Cancer Discov;
10(10): 1500-1513, 2020 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32606137
8.
RUNX1-mutated families show phenotype heterogeneity and a somatic mutation profile unique to germline predisposed AML.
Blood Adv;
4(6): 1131-1144, 2020 03 24.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32208489
9.
The use of appropriate calibration curves corrects for systematic differences in liver R2* values measured using different software packages.
Br J Haematol;
161(6): 888-91, 2013 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23496418
10.
LSD1 Inhibition Prolongs Survival in Mouse Models of MPN by Selectively Targeting the Disease Clone.
Hemasphere;
2(3): e54, 2018 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31723778