Detalhe da pesquisa
1.
A familial missense variant in the Alzheimer's disease gene SORL1 impairs its maturation and endosomal sorting.
Acta Neuropathol;
147(1): 20, 2024 Jan 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38244079
2.
The application of in vitro-derived human neurons in neurodegenerative disease modeling.
J Neurosci Res;
99(1): 124-140, 2021 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32170790
3.
Pharmacologic enhancement of retromer rescues endosomal pathology induced by defects in the Alzheimer's gene SORL1.
Stem Cell Reports;
18(12): 2434-2450, 2023 12 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37949073
4.
Advancements in high-resolution 3D microscopy analysis of endosomal morphology in postmortem Alzheimer's disease brains.
Front Neurosci;
17: 1321680, 2023.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38292900
5.
A familial missense variant in the Alzheimer's Disease gene SORL1 impairs its maturation and endosomal sorting.
bioRxiv;
2023 Nov 13.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37461597
6.
Human microglia show unique transcriptional changes in Alzheimer's disease.
Nat Aging;
3(7): 894-907, 2023 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37248328
7.
The Delayed Neuropathological Consequences of Traumatic Brain Injury in a Community-Based Sample.
Front Neurol;
12: 624696, 2021.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33796061
8.
Comparison of regional flortaucipir PET with quantitative tau immunohistochemistry in three subjects with Alzheimer's disease pathology: a clinicopathological study.
EJNMMI Res;
10(1): 65, 2020 Jun 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32542468
9.
Ophthalmology-Based Neuropathology Risk Factors: Diabetic Retinopathy is Associated with Deep Microinfarcts in a Community-Based Autopsy Study.
J Alzheimers Dis;
68(2): 647-655, 2019.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30883356
10.
Leptomeninges-Derived Induced Pluripotent Stem Cells and Directly Converted Neurons From Autopsy Cases With Varying Neuropathologic Backgrounds.
J Neuropathol Exp Neurol;
77(5): 353-360, 2018 05 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29474672
11.
Neuropathological and transcriptomic characteristics of the aged brain.
Elife;
62017 11 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29120328
12.
Antagonism of neuronal prostaglandin E(2) receptor subtype 1 mitigates amyloid ß neurotoxicity in vitro.
J Neuroimmune Pharmacol;
8(1): 87-93, 2013 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22718277
13.
Novel antibody capture assay for paraffin-embedded tissue detects wide-ranging amyloid beta and paired helical filament-tau accumulation in cognitively normal older adults.
Brain Pathol;
22(4): 472-84, 2012 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21999410
14.
Severely impaired learning and altered neuronal morphology in mice lacking NMDA receptors in medium spiny neurons.
PLoS One;
6(11): e28168, 2011.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22132236
15.
Pathologic correlates of dementia in individuals with Lewy body disease.
Brain Pathol;
20(3): 654-9, 2010 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20522091