Detalhe da pesquisa
1.
The Myc connection: ES cells and cancer.
Cell;
143(2): 184-6, 2010 Oct 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20946977
2.
Population pharmacokinetics and pharmacodynamics of efmarodocokin alfa (IL-22Fc).
J Pharmacokinet Pharmacodyn;
51(2): 141-153, 2024 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37864000
3.
Dose escalation randomised study of efmarodocokin alfa in healthy volunteers and patients with ulcerative colitis.
Gut;
72(8): 1451-1461, 2023 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36732049
4.
A Phase 1, Randomized, Single-Ascending-Dose Study To Investigate the Safety, Tolerability, and Pharmacokinetics of DSTA4637S, an Anti-Staphylococcus aureus Thiomab Antibody-Antibiotic Conjugate, in Healthy Volunteers.
Antimicrob Agents Chemother;
63(6)2019 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30910894
5.
Control of inflammation by stromal Hedgehog pathway activation restrains colitis.
Proc Natl Acad Sci U S A;
113(47): E7545-E7553, 2016 11 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27815529
6.
Quantitative assessment of single-cell RNA-sequencing methods.
Nat Methods;
11(1): 41-6, 2014 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24141493
7.
KIT Signaling Promotes Growth of Colon Xenograft Tumors in Mice and Is Up-Regulated in a Subset of Human Colon Cancers.
Gastroenterology;
149(3): 705-17.e2, 2015 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26026391
8.
Helicobacter pylori Activates and Expands Lgr5(+) Stem Cells Through Direct Colonization of the Gastric Glands.
Gastroenterology;
148(7): 1392-404.e21, 2015 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25725293
9.
Geometry of the Gene Expression Space of Individual Cells.
PLoS Comput Biol;
11(7): e1004224, 2015 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26161936
10.
Innate immune response to homologous rotavirus infection in the small intestinal villous epithelium at single-cell resolution.
Proc Natl Acad Sci U S A;
109(50): 20667-72, 2012 Dec 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23188796
11.
Identification of a cKit(+) colonic crypt base secretory cell that supports Lgr5(+) stem cells in mice.
Gastroenterology;
142(5): 1195-1205.e6, 2012 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22333952
12.
IL-22 alters gut microbiota composition and function to increase aryl hydrocarbon receptor activity in mice and humans.
Microbiome;
11(1): 47, 2023 03 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36894983
13.
A phase I, randomized, ascending-dose study to assess safety, pharmacokinetics, and activity of GDC-8264, a RIP1 inhibitor, in healthy volunteers.
Clin Transl Sci;
16(10): 1997-2009, 2023 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37596814
14.
Inhibition of RIP1 improves immune reconstitution and reduces GVHD mortality while preserving graft-versus-leukemia effects.
Sci Transl Med;
15(727): eadf8366, 2023 12 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38117900
15.
salvador--The persistence of proliferation.
Cancer Cell;
2(3): 171-3, 2002 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12242148
16.
A Phase 1 study of GDC-0134, a dual leucine zipper kinase inhibitor, in ALS.
Ann Clin Transl Neurol;
9(1): 50-66, 2022 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35014217
17.
Randomized Phase I Healthy Volunteer Study of UTTR1147A (IL-22Fc): A Potential Therapy for Epithelial Injury.
Clin Pharmacol Ther;
105(1): 177-189, 2019 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29952004
18.
R-spondin-3 induces secretory, antimicrobial Lgr5+ cells in the stomach.
Nat Cell Biol;
21(7): 812-823, 2019 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31235935
19.
Correction to: Safety, Tolerability, and Pharmacokinetics of GDC-0276, a Novel NaV1.7 Inhibitor, in a First-in-Human, Single- and Multiple-Dose Study in Healthy Volunteers.
Clin Drug Investig;
39(9): 889-890, 2019 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31338799
20.
Safety, Tolerability, and Pharmacokinetics of GDC-0276, a Novel NaV1.7 Inhibitor, in a First-in-Human, Single- and Multiple-Dose Study in Healthy Volunteers.
Clin Drug Investig;
39(9): 873-887, 2019 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31172446