[Study of Stability and Sensitivity of Three-dimensional Diode Array Detector].

PURPOSE: Intensity modulated radiation therapy (IMRT) has become a widely accepted and efficient treatment technique for many types of cancers. Patient's specific quality assurance (QA) should be performed with QA devices. Stability and sensitivity tests conducted on the ArcCHECK (AC) 3D diode array were performed. METHODS: Set-up error test with AC was performed. The set-up position moved to lateral (mm), longitudinal (mm) and rotational (°) were 0.5, 1.0, 2.0 and 3.0, respectively. Sensitivity change test of diode array with AC through 230 days was also performed. Same array calibration data was applied to all measurements of volumetric-modulated arc therapy benchmark test through 230 days. Gamma method (2 mm/2% criteria) was performed to analyze the result of all measurements. RESULTS: In the results of positional error, gamma pass rate become degenerate according to positional error became larger. With 0.5 mm or 0.5° positional error, decreasing rate of the pass rate of lateral, longitudinal and rotational were 1.0%, 2.5% and 4.2%, respectively. In the sensitivity change test, the gamma pass rate decreased 2.2%/100 days with same calibration data. CONCLUSION: AC has highly sensitivity against positional error. Sensitivity of AC has been changed and pass rate was decreased 2.2%/100 days through 230 days. Array calibration should be performed in consideration of change of sensitivity.

[Development of Novel Immobilization Adapter for Head and Neck Radiotherapy with Low-attenuation Material].

PURPOSE: The dosimetric error due to immobilization devices has been highlighted by the AAPM Task Group 176. We developed a novel low-radiation-absorbent immobilization adaptor (HMA), which can be used with a Styrofoam headrest for head and neck region in radiotherapy. The purpose of this study was to investigate the impact of the HMA on the dose distribution and compare with a commercially released plastic adapter. METHODS: Computed tomography (CT) simulation and dose calculation on a treatment planning system (TPS) were performed by the use of HMA and the plastic adapter with a cylindrical phantom. Both the adapters were placed on the phantom upside and the attenuation rate was measured. Gantry angles were changed at every 1°interval from 0°to 50°for measurements. The measured dose was normalized by the value of 90°. The treatment equipment was TrueBeam (Varian medical systems); X-ray energies were set on 4, 6 and 10 MV, respectively. The measured attenuation rates were also compared with calculation results of TPS. RESULTS: The highest differences on attenuation rate of both the adapters were observed at a gantry angle of 32.0°; the differences were 3.0% at 4 MV, 2.7% at 6 MV and 3.0% at 10 MV, respectively, and lower absorption was HMA. TPS calculation results of monitor unit for the HMA were within 1.0% in each energy. CONCLUSION: The HMA was able to provide absorption dose and calculation errors lower than a commercially released adapter. It can also provide more accurate dose delivery for radiotherapy in head and neck because of the low absorption characteristics.

[Quantitative Evaluation of Metal Artifacts on CT Images on the Basis of Statistics of Extremes].

It is well-known that metal artifacts have a harmful effect on the image quality of computed tomography (CT) images. However, the physical property remains still unknown. In this study, we investigated the relationship between metal artifacts and tube currents using statistics of extremes. A commercially available phantom for measuring CT dose index 160 mm in diameter was prepared and a brass rod 13 mm in diameter was placed at the centerline of the phantom. This phantom was used as a target object to evaluate metal artifacts and was scanned using an area detector CT scanner with various tube currents under a constant tube voltage of 120 kV. Sixty parallel line segments with a length of 100 pixels were placed to cross metal artifacts on CT images and the largest difference between two adjacent CT values in each of 60 CT value profiles of these line segments was employed as a feature variable for measuring metal artifacts; these feature variables were analyzed on the basis of extreme value theory. The CT value variation induced by metal artifacts was statistically characterized by Gumbel distribution, which was one of the extreme value distributions; namely, metal artifacts have the same statistical characteristic as streak artifacts. Therefore, Gumbel evaluation method makes it possible to analyze not only streak artifacts but also metal artifacts. Furthermore, the location parameter in Gumbel distribution was shown to be in inverse proportion to the square root of a tube current. This result suggested that metal artifacts have the same dose dependence as image noises.

[Comparison of Bladder Volume Measurement Accuracy between Portable Ultrasound Diagnostic Equipment and CBCT for Pelvic Prostate Radiotherapy].

PURPOSE: We evaluated the measurement accuracy of the CubeScan BioCon-900 (here after BioCon-900), a portable ultrasound imaging diagnostic device capable of measuring bladder volume, to determine if it can accurately assess bladder volume before intensity-modulated radiation therapy (IMRT) for prostate cancer. METHODS: Bladder volume was measured from kV-Cone Beam computed tomography (CBCT) images obtained immediately before the administration of IMRT for prostate cancer using Halcyon. The bladder volume measured from kV-CBCT images (23 patients, total number of scans: 139) immediately before the IMRT procedure was used as the reference value. The difference between the bladder volume measured by the BioCon-900 was then calculated. RESULTS: The bladder volume measured from kV-CBCT images was 117.5±49.4 cc. In contrast, the bladder volume obtained with BioCon-900 was 104.1±48.6 ml, resulting in an absolute mean difference of 18.4% and a correlation coefficient of 0.881. The measurements by BioCon-900 tended to be, on average, 11% smaller than the bladder volume measured by kV-CBCT imaging. CONCLUSION: kV-CBCT images demonstrated a strong positive correlation between bladder volume and bladder urine output obtained with BioCon-900. BioCon-900 can be used before kV-CBCT imaging to accurately and conveniently assess bladder volume.