Detalhe da pesquisa
1.
Structural pharmacology and therapeutic potential of 5-methoxytryptamines.
Nature;
630(8015): 237-246, 2024 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38720072
2.
Molecular Design of SERTlight: A Fluorescent Serotonin Probe for Neuronal Labeling in the Brain.
J Am Chem Soc;
146(14): 9564-9574, 2024 Apr 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38557024
3.
Iboga Inspired N-Indolylethyl-Substituted Isoquinuclidines as a Bioactive Scaffold: Chemoenzymatic Synthesis and Characterization as GDNF Releasers and Antitrypanosoma Agents.
Molecules;
27(3)2022 Jan 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35164094
4.
Chemical Targeting of Voltage Sensitive Dyes to Specific Cells and Molecules in the Brain.
J Am Chem Soc;
142(20): 9285-9301, 2020 05 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32395989
5.
Synthetic and Receptor Signaling Explorations of the Mitragyna Alkaloids: Mitragynine as an Atypical Molecular Framework for Opioid Receptor Modulators.
J Am Chem Soc;
138(21): 6754-64, 2016 06 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27192616
6.
Fluorescent dopamine tracer resolves individual dopaminergic synapses and their activity in the brain.
Proc Natl Acad Sci U S A;
110(3): 870-5, 2013 Jan 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23277566
7.
Accessing Drug Metabolites via Transition-Metal Catalyzed C-H Oxidation: The Liver as Synthetic Inspiration.
Angew Chem Int Ed Engl;
55(46): 14218-14238, 2016 11 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27723189
8.
Paradoxical abatement of striatal dopaminergic transmission by cocaine and methylphenidate.
J Biol Chem;
289(1): 264-74, 2014 Jan 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24280216
9.
Constructing Iboga alkaloids via C-H bond functionalization: examination of the direct and catalytic union of heteroarenes and isoquinuclidine alkenes.
J Org Chem;
80(4): 2062-71, 2015 Feb 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25633249
10.
NeuO: a fluorescent chemical probe for live neuron labeling.
Angew Chem Int Ed Engl;
54(8): 2442-6, 2015 Feb 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25565332
11.
Complementation of biotransformations with chemical C-H oxidation: copper-catalyzed oxidation of tertiary amines in complex pharmaceuticals.
J Am Chem Soc;
135(33): 12346-52, 2013 Aug 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23875728
12.
C-H bonds as ubiquitous functionality: preparation of multiple regioisomers of arylated 1,2,4-triazoles via C-H arylation.
J Org Chem;
78(2): 738-43, 2013 Jan 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23276283
13.
Dopamine transporter and synaptic vesicle sorting defects underlie auxilin-associated Parkinson's disease.
Cell Rep;
42(3): 112231, 2023 03 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36920906
14.
Pharmacological Mechanism of the Non-hallucinogenic 5-HT2A Agonist Ariadne and Analogs.
ACS Chem Neurosci;
14(1): 119-135, 2023 01 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36521179
15.
Catalytic coupling of arene C-H bonds and alkynes for the synthesis of coumarins: substrate scope and application to the development of neuroimaging agents.
J Org Chem;
77(18): 7804-14, 2012 Sep 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22768913
16.
C-H bond functionalization via hydride transfer: formation of α-arylated piperidines and 1,2,3,4-tetrahydroisoquinolines via stereoselective intramolecular amination of benzylic C-H bonds.
J Org Chem;
77(16): 6689-702, 2012 Aug 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22672002
17.
Chemical Targeting of Rhodol Voltage-Sensitive Dyes to Dopaminergic Neurons.
ACS Chem Neurosci;
13(8): 1251-1262, 2022 04 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35400149
18.
C-H arylation of pyridines: high regioselectivity as a consequence of the electronic character of C-H bonds and heteroarene ring.
J Am Chem Soc;
133(41): 16338-41, 2011 Oct 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21939181
19.
Development of a Dual Fluorescent and Magnetic Resonance False Neurotransmitter That Reports Accumulation and Release from Dopaminergic Synaptic Vesicles.
ACS Chem Neurosci;
12(24): 4546-4553, 2021 12 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34817175
20.
Site selective C-H functionalization of Mitragyna alkaloids reveals a molecular switch for tuning opioid receptor signaling efficacy.
Nat Commun;
12(1): 3858, 2021 06 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34158473