1.
Int J Mol Sci
; 23(19)2022 Sep 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36232422
RESUMO
Microwave-assisted reaction between 2-(3-oxoindolin-2-yl)-2-phenylacetonitriles andbenzene-1,2-diamines leads to the high-yielding formation of the corresponding quinoxalines as sole, easily isolaable products. The featured transformation involves unusual extrusion of phenylacetonitrile molecule and could be performed in a short sequence starting from commonly available indoles and nitroolefins.