Detalhe da pesquisa
1.
Immunogenicity profile in African green monkeys of a vaccine candidate based on a mutated form of human Interleukin-15.
BMC Immunol;
22(1): 79, 2021 12 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34922462
2.
Sustained IL-2R signaling of limited duration by high-dose mIL-2/mCD25 fusion protein amplifies tumor-reactive CD8+ T cells to enhance antitumor immunity.
Cancer Immunol Immunother;
70(4): 909-921, 2021 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33037893
3.
In vitro and in vivo characterization of an interleukin-15 antagonist peptide by metabolic stability, 99m Tc-labeling, and biological activity assays.
J Pept Sci;
24(4-5): e3078, 2018 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29656472
4.
Obtention and characterization of the recombinant simian Interleukin-15 in Escherichia coli for the preclinical assessment of an IL-15-based therapeutic vaccine.
Prep Biochem Biotechnol;
47(9): 889-900, 2017 Oct 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28816622
5.
Active immunization with human interleukin-15 induces neutralizing antibodies in non-human primates.
BMC Immunol;
17(1): 30, 2016 Sep 26.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27671547
6.
Differential expression of pro-inflammatory cytokines IL-15Ralpha, IL-15, IL-6 and TNFalpha in synovial fluid from rheumatoid arthritis patients.
BMC Musculoskelet Disord;
16: 51, 2015 Mar 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25879761
7.
Robust IL-2-dependent antitumor immunotherapy requires targeting the high-affinity IL-2R on tumor-specific CD8+ T cells.
J Immunother Cancer;
11(6)2023 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37270181
8.
High-dose IL-2/CD25 fusion protein amplifies vaccine-induced CD4+ and CD8+ neoantigen-specific T cells to promote antitumor immunity.
J Immunother Cancer;
9(9)2021 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34475132
9.
Persistent IL-2 Receptor Signaling by IL-2/CD25 Fusion Protein Controls Diabetes in NOD Mice by Multiple Mechanisms.
Diabetes;
69(11): 2400-2413, 2020 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32843568
10.
Proinflammatory soluble interleukin-15 receptor alpha is increased in rheumatoid arthritis.
Arthritis;
2012: 943156, 2012.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22888423