Detalhe da pesquisa
1.
Clinical mutations in the TERT and TERC genes coding for telomerase components induced oxidative stress, DNA damage at telomeres and cell apoptosis besides decreased telomerase activity.
Hum Mol Genet;
33(9): 818-834, 2024 Apr 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38641551
2.
Gene therapy restores the transcriptional program of hematopoietic stem cells in Fanconi anemia.
Haematologica;
108(10): 2652-2663, 2023 10 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37021532
3.
GSE4-loaded nanoparticles a potential therapy for lung fibrosis that enhances pneumocyte growth, reduces apoptosis and DNA damage.
FASEB J;
35(3): e21422, 2021 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33638895
4.
Shorter telomere length is associated with COVID-19 hospitalization and with persistence of radiographic lung abnormalities.
Immun Ageing;
19(1): 38, 2022 Aug 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35996190
5.
Mutations in XLF/NHEJ1/Cernunnos gene results in downregulation of telomerase genes expression and telomere shortening.
Hum Mol Genet;
26(10): 1900-1914, 2017 05 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28369633
6.
Role of Dusp6 Phosphatase as a Tumor Suppressor in Non-Small Cell Lung Cancer.
Int J Mol Sci;
20(8)2019 Apr 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31027181
7.
Mef2A, a homologue of animal Mef2 transcription factors, regulates cell differentiation in Dictyostelium discoideum.
BMC Dev Biol;
13: 12, 2013 Apr 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23577638
8.
The dual-specificity protein phosphatase MkpB, homologous to mammalian MKP phosphatases, is required for D. discoideum post-aggregative development and cisplatin response.
Differentiation;
81(3): 199-207, 2011 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21300429
9.
Comparison of Colorectal Cancer Stem Cells and Oxaliplatin-Resistant Cells Unveils Functional Similarities.
Cells;
11(3)2022 02 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35159320
10.
Generation of dyskeratosis congenita-like hematopoietic stem cells through the stable inhibition of DKC1.
Stem Cell Res Ther;
12(1): 92, 2021 01 29.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33514435
11.
Next-generation Sequencing in Bone Marrow Failure Syndromes and Isolated Cytopenias: Experience of the Spanish Network on Bone Marrow Failure Syndromes.
Hemasphere;
5(4): e539, 2021 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33718801
12.
SrfB, a member of the Serum Response Factor family of transcription factors, regulates starvation response and early development in Dictyostelium.
Dev Biol;
316(2): 260-74, 2008 Apr 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18339368
13.
Dyskerin Mutations Present in Dyskeratosis Congenita Patients Increase Oxidative Stress and DNA Damage Signalling in Dictyostelium Discoideum.
Cells;
8(11)2019 11 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31717312
14.
Structure of Dictyostelium discoideum telomeres. Analysis of possible replication mechanisms.
PLoS One;
14(9): e0222909, 2019.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31550289
15.
GSE4 peptide suppresses oxidative and telomere deficiencies in ataxia telangiectasia patient cells.
Cell Death Differ;
26(10): 1998-2014, 2019 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30670828
16.
Genetic analyses of aplastic anemia and idiopathic pulmonary fibrosis patients with short telomeres, possible implication of DNA-repair genes.
Orphanet J Rare Dis;
14(1): 82, 2019 04 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30995915
17.
Structural and functional studies of a family of Dictyostelium discoideum developmentally regulated, prestalk genes coding for small proteins.
BMC Microbiol;
8: 1, 2008 Jan 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18173832
18.
Investigating gene expression: in situ hybridization and reporter genes.
Methods Mol Biol;
346: 247-60, 2006.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16957295
19.
Biological Activity of the Alternative Promoters of the Dictyostelium discoideum Adenylyl Cyclase A Gene.
PLoS One;
11(2): e0148533, 2016.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26840347
20.
Regulated expression of the MADS-box transcription factor SrfA mediates activation of gene expression by protein kinase A during Dictyostelium sporulation.
Mech Dev;
117(1-2): 201-8, 2002 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12204259