Detalhe da pesquisa
1.
Mitochondria-dependent synthetic small-molecule vaccine adjuvants for influenza virus infection.
Proc Natl Acad Sci U S A;
118(23)2021 06 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34078669
2.
Structure-activity relationship studies in substituted sulfamoyl benzamidothiazoles that prolong NF-κB activation.
Bioorg Med Chem;
43: 116242, 2021 08 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34274759
3.
Induction of oligoclonal CD8 T cell responses against pulmonary metastatic cancer by a phospholipid-conjugated TLR7 agonist.
Proc Natl Acad Sci U S A;
115(29): E6836-E6844, 2018 07 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29967183
4.
Identification of a Novel Small Molecule That Enhances the Release of Extracellular Vesicles with Immunostimulatory Potency via Induction of Calcium Influx.
ACS Chem Biol;
18(4): 982-993, 2023 04 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37039433
5.
A Triple High Throughput Screening for Extracellular Vesicle Inducing Agents With Immunostimulatory Activity.
Front Pharmacol;
13: 869649, 2022.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35479316
6.
Small Molecule Calcium Channel Activator Potentiates Adjuvant Activity.
ACS Chem Biol;
17(1): 217-229, 2022 01 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34985883
7.
A Dual Adjuvant System for Intranasal Boosting of Local and Systemic Immunity for Influenza Vaccination.
Vaccines (Basel);
10(10)2022 Oct 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36298559
8.
Generation and Application of a Reporter Cell Line for the Quantitative Screen of Extracellular Vesicle Release.
Front Pharmacol;
12: 668609, 2021.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33935791
9.
Small Molecule Potentiator of Adjuvant Activity Enhancing Survival to Influenza Viral Challenge.
Front Immunol;
12: 701445, 2021.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34650551
10.
A Novel Synthetic Dual Agonistic Liposomal TLR4/7 Adjuvant Promotes Broad Immune Responses in an Influenza Vaccine With Minimal Reactogenicity.
Front Immunol;
11: 1207, 2020.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32636840
11.
Structure-Activity Relationship Studies To Identify Affinity Probes in Bis-aryl Sulfonamides That Prolong Immune Stimuli.
J Med Chem;
62(21): 9521-9540, 2019 11 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31603681
12.
Discovery of a Novel Microtubule Targeting Agent as an Adjuvant for Cancer Immunotherapy.
Biomed Res Int;
2018: 8091283, 2018.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30406141
13.
Identification of Compounds That Prolong Type I Interferon Signaling as Potential Vaccine Adjuvants.
SLAS Discov;
23(9): 960-973, 2018 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29751735
14.
Identification of Biologically Active Pyrimido[5,4-b]indoles That Prolong NF-κB Activation without Intrinsic Activity.
ACS Comb Sci;
19(8): 533-543, 2017 08 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28657707
15.
Combination immunotherapy with TLR agonists and checkpoint inhibitors suppresses head and neck cancer.
JCI Insight;
2(18)2017 09 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28931759