Detalhe da pesquisa
1.
Diroximel fumarate in patients with relapsing-remitting multiple sclerosis: Final safety and efficacy results from the phase 3 EVOLVE-MS-1 study.
Mult Scler;
29(14): 1795-1807, 2023 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37905526
2.
Chronic lesion activity and disability progression in secondary progressive multiple sclerosis.
BMJ Neurol Open;
4(1): e000240, 2022.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35720980
3.
Effect of Dimethyl Fumarate vs Interferon ß-1a in Patients With Pediatric-Onset Multiple Sclerosis: The CONNECT Randomized Clinical Trial.
JAMA Netw Open;
5(9): e2230439, 2022 09 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36169959
4.
Safety and Pharmacokinetics of the Oral TYK2 Inhibitor PF-06826647: A Phase I, Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Study.
Clin Transl Sci;
14(2): 671-682, 2021 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33290616
5.
Safety, tolerability, efficacy, pharmacokinetics, and pharmacodynamics of the oral TYK2 inhibitor PF-06826647 in participants with plaque psoriasis: a phase 1, randomised, double-blind, placebo-controlled, parallel-group study.
Lancet Rheumatol;
3(3): e204-e213, 2021 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38279383
6.
Next-generation Bruton's tyrosine kinase inhibitor BIIB091 selectively and potently inhibits B cell and Fc receptor signaling and downstream functions in B cells and myeloid cells.
Clin Transl Immunology;
10(6): e1295, 2021.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34141433
7.
Molecular and Cellular Responses to the TYK2/JAK1 Inhibitor PF-06700841 Reveal Reduction of Skin Inflammation in Plaque Psoriasis.
J Invest Dermatol;
140(8): 1546-1555.e4, 2020 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31972249
8.
Reward circuitry in resilience to severe trauma: an fMRI investigation of resilient special forces soldiers.
Psychiatry Res;
172(1): 75-7, 2009 Apr 30.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19243926
9.
The Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a TYK2/JAK1 Inhibitor (PF-06700841) in Healthy Subjects and Patients With Plaque Psoriasis.
J Clin Pharmacol;
58(4): 434-447, 2018 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29266308
10.
Effect of oral cladribine on time to conversion to clinically definite multiple sclerosis in patients with a first demyelinating event (ORACLE MS): a phase 3 randomised trial.
Lancet Neurol;
13(3): 257-67, 2014 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24502830
11.
Cladribine tablets for the treatment of relapsing-remitting multiple sclerosis.
Expert Opin Pharmacother;
14(1): 123-36, 2013 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23256518