Detalhe da pesquisa
1.
An exploratory study on the effect of mechanical stress on particle formation in monoclonal antibody infusions.
Arch Pharm (Weinheim);
356(8): e2300101, 2023 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37224805
2.
Discovery of 3-Amino-1H-pyrazole-Based Kinase Inhibitors to Illuminate the Understudied PCTAIRE Family.
Int J Mol Sci;
23(23)2022 Nov 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36499165
3.
Structure optimization of a new class of PPARγ antagonists.
Bioorg Med Chem;
27(21): 115082, 2019 11 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31548084
4.
Transepithelial Transport of Curcumin in Caco-2 Cells Is significantly Enhanced by Micellar Solubilisation.
Plant Foods Hum Nutr;
72(1): 48-53, 2017 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27900602
5.
MH84: A Novel γ-Secretase Modulator/PPARγ Agonist--Improves Mitochondrial Dysfunction in a Cellular Model of Alzheimer's Disease.
Neurochem Res;
41(1-2): 231-42, 2016 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26721513
6.
Letter to the Editor regarding "Comparison of phytochemical composition of Ginkgo biloba extracts using a combination of non-targeted and targeted analytical approaches".
Anal Bioanal Chem;
413(30): 7625-7626, 2021 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34716782
7.
Survey on the Quality of the Top-Selling European and American Botanical Dietary Supplements Containing Boswellic Acids.
Planta Med;
82(6): 573-9, 2016 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27054914
8.
SAR-studies of γ-secretase modulators with PPARγ-agonistic and 5-lipoxygenase-inhibitory activity for Alzheimer's disease.
Bioorg Med Chem Lett;
25(4): 841-6, 2015 Feb 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25575659
9.
Anthranilic acid derivatives as nuclear receptor modulators--development of novel PPAR selective and dual PPAR/FXR ligands.
Bioorg Med Chem;
23(3): 499-514, 2015 Feb 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25583100
10.
Fragmentation of GW4064 led to a highly potent partial farnesoid X receptor agonist with improved drug-like properties.
Bioorg Med Chem;
23(13): 3490-8, 2015 Jul 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25934227
11.
Molecular determinants for improved activity at PPARα: structure-activity relationship of pirinixic acid derivatives, docking study and site-directed mutagenesis of PPARα.
Bioorg Med Chem Lett;
24(16): 4048-52, 2014 Aug 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25022880
12.
Identification of pirinixic acid derivatives bearing a 2-aminothiazole moiety combines dual PPARα/γ activation and dual 5-LO/mPGES-1 inhibition.
Bioorg Med Chem Lett;
24(16): 3757-63, 2014 Aug 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25037914
13.
Vanillin-derived antiproliferative compounds influence Plk1 activity.
Bioorg Med Chem Lett;
24(21): 5063-9, 2014 Nov 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25304894
14.
Anthranilic acid derivatives as novel ligands for farnesoid X receptor (FXR).
Bioorg Med Chem;
22(8): 2447-60, 2014 Apr 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24685112
15.
Synthesis of Pyrazole-Based Macrocycles Leads to a Highly Selective Inhibitor for MST3.
J Med Chem;
67(1): 674-690, 2024 Jan 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38126712
16.
Synthesis and pharmacological characterization of benzenesulfonamides as dual species inhibitors of human and murine mPGES-1.
Bioorg Med Chem;
21(24): 7874-83, 2013 Dec 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24183739
17.
Rational Design of a New RXR Agonist Scaffold Enabling Single-Subtype Preference for RXRα, RXRß, and RXRγ.
J Med Chem;
66(1): 333-344, 2023 01 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36533416
18.
Structural Fusion of Natural and Synthetic Ligand Features Boosts RXR Agonist Potency.
J Med Chem;
66(24): 16762-16771, 2023 12 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38064686
19.
SAR-study on a new class of imidazo[1,2-a]pyridine-based inhibitors of 5-lipoxygenase.
Bioorg Med Chem Lett;
22(5): 1969-75, 2012 Mar 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22326163
20.
Effect of phospholipid-based formulations of Boswellia serrata extract on the solubility, permeability, and absorption of the individual boswellic acid constituents present.
J Nat Prod;
75(10): 1675-82, 2012 Oct 26.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23013292