Detalhe da pesquisa
1.
Midbrain organoids mimic early embryonic neurodevelopment and recapitulate LRRK2-p.Gly2019Ser-associated gene expression.
Am J Hum Genet;
109(2): 311-327, 2022 02 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35077669
2.
Alpha-synuclein pathology is associated with astrocyte senescence in a midbrain organoid model of familial Parkinson's disease.
Mol Cell Neurosci;
128: 103919, 2024 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38307302
3.
The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors.
Cell;
136(5): 913-25, 2009 Mar 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19269368
4.
Single-cell sequencing of human midbrain reveals glial activation and a Parkinson-specific neuronal state.
Brain;
145(3): 964-978, 2022 04 29.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34919646
5.
Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality.
Glia;
70(7): 1267-1288, 2022 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35262217
6.
Impaired mitochondrial-endoplasmic reticulum interaction and mitophagy in Miro1-mutant neurons in Parkinson's disease.
Hum Mol Genet;
29(8): 1353-1364, 2020 05 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32280985
7.
Parkinson's Disease Phenotypes in Patient Neuronal Cultures and Brain Organoids Improved by 2-Hydroxypropyl-ß-Cyclodextrin Treatment.
Mov Disord;
37(1): 80-94, 2022 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34637165
8.
Nuclear localization and phosphorylation modulate pathological effects of alpha-synuclein.
Hum Mol Genet;
28(1): 31-50, 2019 01 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30219847
9.
Mitochondrial and Clearance Impairment in p.D620N VPS35 Patient-Derived Neurons.
Mov Disord;
36(3): 704-715, 2021 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33142012
10.
Monitoring the neurotransmitter release of human midbrain organoids using a redox cycling microsensor as a novel tool for personalized Parkinson's disease modelling and drug screening.
Analyst;
146(7): 2358-2367, 2021 Apr 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33625407
11.
Absence of TRIM32 Leads to Reduced GABAergic Interneuron Generation and Autism-like Behaviors in Mice via Suppressing mTOR Signaling.
Cereb Cortex;
30(5): 3240-3258, 2020 05 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31828304
12.
A human stem cell-derived test system for agents modifying neuronal N-methyl-D-aspartate-type glutamate receptor Ca2+-signalling.
Arch Toxicol;
95(5): 1703-1722, 2021 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33713149
13.
Transition metal dichalcogenides to optimize the performance of peptide-imprinted conductive polymers as electrochemical sensors.
Mikrochim Acta;
188(6): 203, 2021 05 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34043106
14.
Single-cell transcriptomics reveals multiple neuronal cell types in human midbrain-specific organoids.
Cell Tissue Res;
382(3): 463-476, 2020 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32737576
15.
Environmental enrichment and physical exercise revert behavioral and electrophysiological impairments caused by reduced adult neurogenesis.
Hippocampus;
27(1): 36-51, 2017 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27701786
16.
Correction: The stimulation of dendrite growth by Sema3A requires integrin engagement and focal adhesion kinase (doi:10.1242/jcs.038232).
J Cell Sci;
133(2)2020 01 23.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31974278
17.
TRIM32 Senses and Restricts Influenza A Virus by Ubiquitination of PB1 Polymerase.
PLoS Pathog;
11(6): e1004960, 2015 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26057645
18.
Prox1 Is Required for Oligodendrocyte Cell Identity in Adult Neural Stem Cells of the Subventricular Zone.
Stem Cells;
34(8): 2115-29, 2016 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27068685
19.
The RNA helicase DDX6 regulates cell-fate specification in neural stem cells via miRNAs.
Nucleic Acids Res;
43(5): 2638-54, 2015 Mar 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25722370
20.
6-hydroxydopamine-induced Parkinson's disease-like degeneration generates acute microgliosis and astrogliosis in the nigrostriatal system but no bioluminescence imaging-detectable alteration in adult neurogenesis.
Eur J Neurosci;
43(10): 1352-65, 2016 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26950181