Detalhe da pesquisa
1.
A Neutralizing IL-11 Antibody Improves Renal Function and Increases Lifespan in a Mouse Model of Alport Syndrome.
J Am Soc Nephrol;
33(4): 718-730, 2022 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35140116
2.
IL11 Activates Pancreatic Stellate Cells and Causes Pancreatic Inflammation, Fibrosis and Atrophy in a Mouse Model of Pancreatitis.
Int J Mol Sci;
23(7)2022 Mar 24.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35408908
3.
Hepatocyte Specific gp130 Signalling Underlies APAP Induced Liver Injury.
Int J Mol Sci;
23(13)2022 Jun 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35806094
4.
IL11 stimulates ERK/P90RSK to inhibit LKB1/AMPK and activate mTOR initiating a mesenchymal program in stromal, epithelial, and cancer cells.
iScience;
25(8): 104806, 2022 Aug 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35992082
5.
Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease.
Nat Commun;
13(1): 7497, 2022 12 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36470928
6.
Similarities and differences between IL11 and IL11RA1 knockout mice for lung fibro-inflammation, fertility and craniosynostosis.
Sci Rep;
11(1): 14088, 2021 07 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34239012
7.
Molecular Dissection of Pro-Fibrotic IL11 Signaling in Cardiac and Pulmonary Fibroblasts.
Front Mol Biosci;
8: 740650, 2021.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34651016
8.
Redefining IL11 as a regeneration-limiting hepatotoxin and therapeutic target in acetaminophen-induced liver injury.
Sci Transl Med;
13(597)2021 06 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34108253
9.
Hepatocyte-specific IL11 cis-signaling drives lipotoxicity and underlies the transition from NAFLD to NASH.
Nat Commun;
12(1): 66, 2021 01 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33397952