Detalhe da pesquisa
1.
Role of Transporters and Enzymes in Metabolism and Distribution of 4-Chlorokynurenine (AV-101).
Mol Pharm;
21(2): 550-563, 2024 Feb 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38261609
2.
Kinase inhibitor-induced cardiotoxicity assessed in vitro with human pluripotent stem cell derived cardiomyocytes.
Toxicol Appl Pharmacol;
437: 115886, 2022 02 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35041852
3.
Probenecid Increases the Concentration of 7-Chlorokynurenic Acid Derived from the Prodrug 4-Chlorokynurenine within the Prefrontal Cortex.
Mol Pharm;
18(1): 113-123, 2021 01 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33307708
4.
A Randomized Trial of the N-Methyl-d-Aspartate Receptor Glycine Site Antagonist Prodrug 4-Chlorokynurenine in Treatment-Resistant Depression.
Int J Neuropsychopharmacol;
23(7): 417-425, 2020 07 29.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32236521
5.
The Prodrug 4-Chlorokynurenine Causes Ketamine-Like Antidepressant Effects, but Not Side Effects, by NMDA/GlycineB-Site Inhibition.
J Pharmacol Exp Ther;
355(1): 76-85, 2015 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26265321
6.
Ectopic expression of the proto-oncogene Mer in pediatric T-cell acute lymphoblastic leukemia.
Clin Cancer Res;
12(9): 2662-9, 2006 May 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16675557
7.
Characterization of the Effects of L-4-Chlorokynurenine on Nociception in Rodents.
J Pain;
18(10): 1184-1196, 2017 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28428091
8.
Randomized, double-blind, placebo-controlled, dose-escalation study: Investigation of the safety, pharmacokinetics, and antihyperalgesic activity of l-4-chlorokynurenine in healthy volunteers.
Scand J Pain;
17: 243-251, 2017 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29229209
9.
Tissue-engineered cardiac patch for advanced functional maturation of human ESC-derived cardiomyocytes.
Biomaterials;
34(23): 5813-20, 2013 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23642535