Detalhe da pesquisa
1.
Characterization of structural, biochemical, pharmacokinetic, and pharmacodynamic properties of the LSD1 inhibitor bomedemstat in preclinical models.
Prostate;
2024 Apr 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38619005
2.
Touch, act and go: landing and operating on nucleosomes.
EMBO J;
35(4): 376-88, 2016 Feb 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26787641
3.
LSD1/KDM1A mutations associated to a newly described form of intellectual disability impair demethylase activity and binding to transcription factors.
Hum Mol Genet;
25(12): 2578-2587, 2016 06 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27094131
4.
Interplay among nucleosomal DNA, histone tails, and corepressor CoREST underlies LSD1-mediated H3 demethylation.
Proc Natl Acad Sci U S A;
112(9): 2752-7, 2015 Mar 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25730864
5.
Probing the interaction of the p53 C-terminal domain to the histone demethylase LSD1.
Arch Biochem Biophys;
632: 202-208, 2017 10 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28784588
6.
Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep;
42(1): 111901, 2023 01 31.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36596301
7.
Nanobodies counteract the toxicity of an amyloidogenic light chain by stabilizing a partially open dimeric conformation.
J Mol Biol;
435(24): 168320, 2023 12 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37865287
8.
Cryo-EM structure of ex vivo fibrils associated with extreme AA amyloidosis prevalence in a cat shelter.
Nat Commun;
13(1): 7041, 2022 11 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36396658
9.
An N-glycosylation hotspot in immunoglobulin κ light chains is associated with AL amyloidosis.
Leukemia;
36(8): 2076-2085, 2022 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35610346
10.
Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil.
Sci Rep;
8(1): 9633, 2018 06 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29941893
11.
Catalysis and Structure of Zebrafish Urate Oxidase Provide Insights into the Origin of Hyperuricemia in Hominoids.
Sci Rep;
6: 38302, 2016 12 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27922051
12.
Polymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structural features.
Sci Adv;
2(9): e1601017, 2016 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27626075