Detalhe da pesquisa
1.
Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists.
Mol Cell;
80(3): 485-500.e7, 2020 11 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33027691
2.
Targeting Adenosine Receptor Signaling in Cancer Immunotherapy.
Int J Mol Sci;
19(12)2018 Dec 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30513816
3.
Sex-Dependent Attentional Impairments in a Subchronic Ketamine Mouse Model for Schizophrenia.
Biol Psychiatry Glob Open Sci;
4(1): 229-239, 2024 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38298794
4.
Molecular insights into orphan G protein-coupled receptors relevant to schizophrenia.
Br J Pharmacol;
2023 Aug 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37605621
5.
Molecular and structural insights into the 5-HT2C receptor as a therapeutic target for substance use disorders.
Br J Pharmacol;
2023 Sep 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37679998
6.
Gpr88 Deletion Impacts Motivational Control Without Overt Disruptions to Striatal Dopamine.
Biol Psychiatry Glob Open Sci;
3(4): 1053-1061, 2023 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37881541
7.
Beyond antipsychotics: a twenty-first century update for preclinical development of schizophrenia therapeutics.
Transl Psychiatry;
12(1): 147, 2022 04 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35393394
8.
Targeting appetite and satiety in diabetes and obesity, via G protein-coupled receptors.
Biochem Pharmacol;
202: 115115, 2022 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35671790
9.
CRISPR/Cas9 mediated deletion of the adenosine A2A receptor enhances CAR T cell efficacy.
Nat Commun;
12(1): 3236, 2021 05 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34050151
10.
Prediction of functionally selective allosteric interactions at an M3 muscarinic acetylcholine receptor mutant using Saccharomyces cerevisiae.
Mol Pharmacol;
78(2): 205-14, 2010 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20466821
11.
ß-Arrestin-2-Dependent Mechanism of GPR52 Signaling in Frontal Cortical Neurons.
ACS Chem Neurosci;
11(14): 2077-2084, 2020 07 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32519845
12.
Translation-Focused Approaches to GPCR Drug Discovery for Cognitive Impairments Associated with Schizophrenia.
ACS Pharmacol Transl Sci;
3(6): 1042-1062, 2020 Dec 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33344888
13.
In the Loop: Extrastriatal Regulation of Spiny Projection Neurons by GPR52.
ACS Chem Neurosci;
11(14): 2066-2076, 2020 07 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32519838
14.
Determination of adenosine A1 receptor agonist and antagonist pharmacology using Saccharomyces cerevisiae: implications for ligand screening and functional selectivity.
J Pharmacol Exp Ther;
331(1): 277-86, 2009 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19641164
15.
A pH-responsive nanoparticle targets the neurokinin 1 receptor in endosomes to prevent chronic pain.
Nat Nanotechnol;
14(12): 1150-1159, 2019 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31686009
16.
Allosteric interactions between GABAB1 subunits control orthosteric binding sites occupancy within GABAB oligomers.
Neuropharmacology;
136(Pt A): 92-101, 2018 07 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29305121
17.
Biased allosteric agonism and modulation of metabotropic glutamate receptor 5: Implications for optimizing preclinical neuroscience drug discovery.
Neuropharmacology;
115: 60-72, 2017 03 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27392634
18.
Murine GPRC6A Mediates Cellular Responses to L-Amino Acids, but Not Osteocalcin Variants.
PLoS One;
11(1): e0146846, 2016.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26785252
19.
Detection of novel functional selectivity at M3 muscarinic acetylcholine receptors using a Saccharomyces cerevisiae platform.
ACS Chem Biol;
5(4): 365-75, 2010 Apr 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20155933
20.
Pharmacology of 5HT(2C) receptor-mediated ERK1/2 phosphorylation: agonist-specific activation pathways and the impact of RNA editing.
Biochem Pharmacol;
76(10): 1276-87, 2008 Nov 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18812172