Detalhe da pesquisa
1.
Abnormal joint and bone wound healing in hemophilia mice is improved by extending factor IX activity after hemarthrosis.
Blood;
129(15): 2161-2171, 2017 04 13.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28039188
2.
Anti-inflammatory effect of a novel piperazino-enaminone delivered by liposomes in a mouse model of hemophilic arthropathy.
Int J Pharm;
659: 124291, 2024 May 29.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38821434
3.
Glycan binding avidity determines the systemic fate of adeno-associated virus type 9.
J Virol;
86(19): 10408-17, 2012 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22787229
4.
A socio-ecological model of factors influencing physical activity in pregnant women: a systematic review.
Front Public Health;
11: 1232625, 2023.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38054068
5.
Intra-articular delivery of AAV vectors encoding PD-L1 attenuates joint inflammation and tissue damage in a mouse model of rheumatoid arthritis.
Front Immunol;
14: 1116084, 2023.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36936967
6.
Cellular immune response to cryptic epitopes during therapeutic gene transfer.
Proc Natl Acad Sci U S A;
106(26): 10770-4, 2009 Jun 30.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19541644
7.
Repeated Systemic Dosing of Adeno-Associated Virus Vectors in Immunocompetent Mice After Blockade of T Cell Costimulatory Pathways.
Hum Gene Ther;
33(5-6): 290-300, 2022 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34486389
8.
Adeno-associated virus-mediated expression of activated factor V (FVa) for hemophilia phenotypic correction.
Front Med (Lausanne);
9: 880763, 2022.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35991645
9.
Chimeric Mice Engrafted With Canine Hepatocytes Exhibits Similar AAV Transduction Efficiency to Hemophilia B Dog.
Front Pharmacol;
13: 815317, 2022.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35173619
10.
[Study on the Therapeutic Effect of Lenalidomide on Hemophilic Arthropathy].
Zhongguo Shi Yan Xue Ye Xue Za Zhi;
30(5): 1549-1556, 2022 Oct.
Artigo
em Zh
| MEDLINE
| ID: mdl-36208264
11.
Low-dose AAV-CRISPR-mediated liver-specific knock-in restored hemostasis in neonatal hemophilia B mice with subtle antibody response.
Nat Commun;
13(1): 7275, 2022 11 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36434000
12.
Safety and activity of an engineered, liver-tropic adeno-associated virus vector expressing a hyperactive Padua factor IX administered with prophylactic glucocorticoids in patients with haemophilia B: a single-centre, single-arm, phase 1, pilot trial.
Lancet Haematol;
9(7): e504-e513, 2022 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35598604
13.
Proteasome inhibitors enhance gene delivery by AAV virus vectors expressing large genomes in hemophilia mouse and dog models: a strategy for broad clinical application.
Mol Ther;
18(11): 1907-16, 2010 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20700109
14.
Naive haemophilia mice displayed different pattern of cytokine profiles of cytokine profiles changes might be associated with subclinical bleeding.
Blood Coagul Fibrinolysis;
32(8): 584-590, 2021 Dec 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34693916
15.
VHL and PTEN loss coordinate to promote mouse liver vascular lesions.
Angiogenesis;
13(1): 59-69, 2010 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20221685
16.
Intraarticular factor IX protein or gene replacement protects against development of hemophilic synovitis in the absence of circulating factor IX.
Blood;
112(12): 4532-41, 2008 Dec 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18716130
17.
Exploring the Potential Feasibility of Intra-Articular Adeno-Associated Virus-Mediated Gene Therapy for Hemophilia Arthropathy.
Hum Gene Ther;
31(7-8): 448-458, 2020 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32079420
18.
Optimization of self-complementary AAV vectors for liver-directed expression results in sustained correction of hemophilia B at low vector dose.
Mol Ther;
16(2): 280-9, 2008 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18059373
19.
Timely and large dose of clotting factor IX provides better joint wound healing after hemarthrosis in hemophilia B mice.
Int J Hematol;
110(1): 59-68, 2019 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31006077
20.
A Translational Study of TNF-Alpha Antagonists as an Adjunctive Therapy for Preventing Hemophilic Arthropathy.
J Clin Med;
9(1)2019 Dec 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31892201