Detalhe da pesquisa
1.
Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques.
Cell;
184(2): 460-475.e21, 2021 01 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33278358
2.
SOX11 is a novel binding partner and endogenous inhibitor of SAMHD1 ara-CTPase activity in mantle cell lymphoma.
Blood;
143(19): 1953-1964, 2024 Jan 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38774451
3.
SOX11 is a novel binding partner and endogenous inhibitor of SAMHD1 ara-CTPase activity in mantle cell lymphoma.
Blood;
143(19): 1953-1964, 2024 May 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38237141
4.
Light-strand bias and enriched zones of embedded ribonucleotides are associated with DNA replication and transcription in the human-mitochondrial genome.
Nucleic Acids Res;
52(3): 1207-1225, 2024 Feb 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38117983
5.
Vpx requires active cellular dNTP biosynthesis to effectively counteract the anti-lentivirus activity of SAMHD1 in macrophages.
J Biol Chem;
299(8): 104984, 2023 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37390988
6.
Synthesis and evaluation of highly potent HBV capsid assembly modulators (CAMs).
Bioorg Chem;
141: 106923, 2023 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37871391
7.
Targeting SAMHD1 with hydroxyurea in first-line cytarabine-based therapy of newly diagnosed acute myeloid leukaemia: Results from the HEAT-AML trial.
J Intern Med;
292(6): 925-940, 2022 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35934913
8.
Novel Hepatitis B Virus Capsid Assembly Modulator Induces Potent Antiviral Responses In Vitro and in Humanized Mice.
Antimicrob Agents Chemother;
64(2)2020 01 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31712213
9.
Template-assisted synthesis of adenine-mutagenized cDNA by a retroelement protein complex.
Nucleic Acids Res;
46(18): 9711-9725, 2018 10 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30007279
10.
Nucleoside Analogs with Antiviral Activity against Yellow Fever Virus.
Antimicrob Agents Chemother;
63(9)2019 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31262759
11.
Baricitinib reverses HIV-associated neurocognitive disorders in a SCID mouse model and reservoir seeding in vitro.
J Neuroinflammation;
16(1): 182, 2019 Sep 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31561750
12.
Characterization of ß-d-N4-Hydroxycytidine as a Novel Inhibitor of Chikungunya Virus.
Antimicrob Agents Chemother;
61(4)2017 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28137799
13.
Pharmacokinetics and Placental Transfer of Elvitegravir, Dolutegravir, and Other Antiretrovirals during Pregnancy.
Antimicrob Agents Chemother;
61(6)2017 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28348149
14.
The Janus kinase inhibitor ruxolitinib reduces HIV replication in human macrophages and ameliorates HIV encephalitis in a murine model.
Neurobiol Dis;
92(Pt B): 137-43, 2016 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26851503
15.
Biochemical Characterization of the Active Anti-Hepatitis C Virus Metabolites of 2,6-Diaminopurine Ribonucleoside Prodrug Compared to Sofosbuvir and BMS-986094.
Antimicrob Agents Chemother;
60(8): 4659-69, 2016 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27216050
16.
Erratum for Amblard et al., "Novel Hepatitis B Virus Capsid Assembly Modulator Induces Potent Antiviral Responses In Vitro and in Humanized Mice".
Antimicrob Agents Chemother;
64(9)2020 08 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32819965
17.
Design, synthesis and evaluation of novel anti-HCV molecules that deliver intracellularly three highly potent NS5A inhibitors.
Bioorg Med Chem Lett;
25(17): 3711-5, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26099532
18.
dNTP pool modulation dynamics by SAMHD1 protein in monocyte-derived macrophages.
Retrovirology;
11: 63, 2014 Aug 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25158827
19.
Randomized, double-blind, multicenter safety and efficacy study of rifalazil compared with azithromycin for treatment of uncomplicated genital Chlamydia trachomatis infection in women.
Antimicrob Agents Chemother;
58(7): 4014-9, 2014 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24798277
20.
Enhanced antiretroviral therapy in rhesus macaques improves RT-SHIV viral decay kinetics.
Antimicrob Agents Chemother;
58(7): 3927-33, 2014 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24777106