Detalhe da pesquisa
1.
Endothelial deficiency of insulin-like growth factor-1 receptor leads to blood-brain barrier disruption and accelerated endothelial senescence in mice, mimicking aspects of the brain aging phenotype.
Microcirculation;
31(2): e12840, 2024 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38082450
2.
Microvascular dysfunction and neurovascular uncoupling are exacerbated in peripheral artery disease, increasing the risk of cognitive decline in older adults.
Am J Physiol Heart Circ Physiol;
322(6): H924-H935, 2022 06 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35333116
3.
Obesity-induced cognitive impairment in older adults: a microvascular perspective.
Am J Physiol Heart Circ Physiol;
320(2): H740-H761, 2021 02 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33337961
4.
Demonstration of age-related blood-brain barrier disruption and cerebromicrovascular rarefaction in mice by longitudinal intravital two-photon microscopy and optical coherence tomography.
Am J Physiol Heart Circ Physiol;
320(4): H1370-H1392, 2021 04 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33543687
5.
Mechanisms of Vascular Aging.
Circ Res;
123(7): 849-867, 2018 09 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30355080
6.
Role of endothelial NAD+ deficiency in age-related vascular dysfunction.
Am J Physiol Heart Circ Physiol;
316(6): H1253-H1266, 2019 06 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30875255
7.
Role of age-related alterations of the cerebral venous circulation in the pathogenesis of vascular cognitive impairment.
Am J Physiol Heart Circ Physiol;
316(5): H1124-H1140, 2019 05 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30848677
8.
Functional vascular contributions to cognitive impairment and dementia: mechanisms and consequences of cerebral autoregulatory dysfunction, endothelial impairment, and neurovascular uncoupling in aging.
Am J Physiol Heart Circ Physiol;
312(1): H1-H20, 2017 Jan 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27793855
9.
Cerebral microhemorrhages: mechanisms, consequences, and prevention.
Am J Physiol Heart Circ Physiol;
312(6): H1128-H1143, 2017 Jun 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28314762
10.
Purinergic glio-endothelial coupling during neuronal activity: role of P2Y1 receptors and eNOS in functional hyperemia in the mouse somatosensory cortex.
Am J Physiol Heart Circ Physiol;
309(11): H1837-45, 2015 Dec 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26453330
11.
Resveratrol treatment rescues neurovascular coupling in aged mice: role of improved cerebromicrovascular endothelial function and downregulation of NADPH oxidase.
Am J Physiol Heart Circ Physiol;
306(3): H299-308, 2014 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24322615
12.
Caloric restriction confers persistent anti-oxidative, pro-angiogenic, and anti-inflammatory effects and promotes anti-aging miRNA expression profile in cerebromicrovascular endothelial cells of aged rats.
Am J Physiol Heart Circ Physiol;
307(3): H292-306, 2014 Aug 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24906921
13.
PCSK9: an emerging player in cardiometabolic aging and its potential as a therapeutic target and biomarker.
Geroscience;
46(1): 257-263, 2024 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38105401
14.
Accelerated Aging Induced by an Unhealthy High-Fat Diet: Initial Evidence for the Role of Nrf2 Deficiency and Impaired Stress Resilience in Cellular Senescence.
Nutrients;
16(7)2024 Mar 26.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38612986
15.
Whole brain irradiation-induced endothelial dysfunction in the mouse brain.
Geroscience;
46(1): 531-541, 2024 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37953375
16.
Exploring the Influence of Gut-Brain Axis Modulation on Cognitive Health: A Comprehensive Review of Prebiotics, Probiotics, and Symbiotics.
Nutrients;
16(6)2024 Mar 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38542700
17.
Irradiation-induced hair graying in mice: an experimental model to evaluate the effectiveness of interventions targeting oxidative stress, DNA damage prevention, and cellular senescence.
Geroscience;
46(3): 3105-3122, 2024 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38182857
18.
Preventing spontaneous cerebral microhemorrhages in aging mice: a novel approach targeting cellular senescence with ABT263/navitoclax.
Geroscience;
46(1): 21-37, 2024 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38044400
19.
Young blood-mediated cerebromicrovascular rejuvenation through heterochronic parabiosis: enhancing blood-brain barrier integrity and capillarization in the aged mouse brain.
Geroscience;
2024 May 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38727872
20.
Atherosclerotic burden and cerebral small vessel disease: exploring the link through microvascular aging and cerebral microhemorrhages.
Geroscience;
2024 Apr 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38639833