Detalhe da pesquisa
1.
Evaluation of the applicability of existing (Q)SAR models for predicting the genotoxicity of pesticides and similarity analysis related with genotoxicity of pesticides for facilitating of grouping and read across: An EFSA funded project.
Regul Toxicol Pharmacol;
114: 104658, 2020 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32334037
2.
Improvement of quantitative structure-activity relationship (QSAR) tools for predicting Ames mutagenicity: outcomes of the Ames/QSAR International Challenge Project.
Mutagenesis;
34(1): 3-16, 2019 03 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30357358
3.
Endocrine Disruptors: Data-based survey of in vivo tests, predictive models and the Adverse Outcome Pathway.
Regul Toxicol Pharmacol;
86: 18-24, 2017 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28232102
4.
A data-based exploration of the adverse outcome pathway for skin sensitization points to the necessary requirements for its prediction with alternative methods.
Regul Toxicol Pharmacol;
78: 45-52, 2016 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27090483
5.
Alternative Toxicity Testing: Analyses on Skin Sensitization, ToxCast Phases I and II, and Carcinogenicity Provide Indications on How to Model Mechanisms Linked to Adverse Outcome Pathways.
J Environ Sci Health C Environ Carcinog Ecotoxicol Rev;
33(4): 422-43, 2015.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26398111
6.
In vitro cell transformation assays for an integrated, alternative assessment of carcinogenicity: a data-based analysis.
Mutagenesis;
28(1): 107-16, 2013 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23132285
7.
New perspectives in toxicological information management, and the role of ISSTOX databases in assessing chemical mutagenicity and carcinogenicity.
Mutagenesis;
28(4): 401-9, 2013 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23470317
8.
IARC classes 1 and 2 carcinogens are successfully identified by an alternative strategy that detects DNA-reactivity and cell transformation ability of chemicals.
Mutat Res Genet Toxicol Environ Mutagen;
758(1-2): 56-61, 2013 Dec 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24076401
9.
Protocol for designing INVITES-IN, a tool for assessing the internal validity of in vitro studies.
Evid Based Toxicol;
1(1): 1-15, 2023 Aug 31.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38264543
10.
The new ISSMIC database on in vivo micronucleus and its role in assessing genotoxicity testing strategies.
Mutagenesis;
27(1): 87-92, 2012 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21965461
11.
Molecular characterization of rotavirus strains from children with diarrhea in Italy, 2007-2009.
J Med Virol;
83(9): 1657-68, 2011 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21739459
12.
Toward regulatory acceptance and improving the prediction confidence of in silico approaches: a case study of genotoxicity.
Expert Opin Drug Metab Toxicol;
17(8): 987-1005, 2021 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34078212
13.
Exploring in vitro/in vivo correlation: lessons learned from analyzing phase I results of the US EPA's ToxCast Project.
J Environ Sci Health C Environ Carcinog Ecotoxicol Rev;
28(4): 272-86, 2010 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21069615
14.
Nongenotoxic carcinogenicity of chemicals: mechanisms of action and early recognition through a new set of structural alerts.
Chem Rev;
113(5): 2940-57, 2013 May 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23469814
15.
A pre-existing population of ZEB2+ quiescent cells with stemness and mesenchymal features dictate chemoresistance in colorectal cancer.
J Exp Clin Cancer Res;
39(1): 2, 2020 Jan 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31910865
16.
PROFALIGN algorithm identifies the regions containing folding determinants by scoring pairs of hydrophobic profiles of remotely related proteins.
J Comput Biol;
15(4): 445-55, 2008 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18386966
17.
(Q)SAR Methods for Predicting Genotoxicity and Carcinogenicity: Scientific Rationale and Regulatory Frameworks.
Methods Mol Biol;
1800: 447-473, 2018.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29934905
18.
Target determination and suspect screening of legacy and emerging per- and poly-fluoro poly-ethers in wild boar liver, in Italy.
Chemosphere;
312(Pt 1): 137214, 2023 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36375613
19.
The challenge of complexity in the Big Data era: how to ride the wave of high-dimensional data revolution. Editorial.
Ann Ist Super Sanita;
58(3): 151-153, 2022.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36128961
20.
Application of computational methods in replacement - an IPAM webinar.
ALTEX;
38(2): 348-350, 2021.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33882578