Detalhe da pesquisa
1.
Comparative pharmacokinetics and pharmacodynamics of intravenous artelinate versus artesunate in uncomplicated Plasmodium coatneyi-infected rhesus monkey model.
Malar J;
15: 453, 2016 09 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27599723
2.
Ex Vivo Drug Susceptibility Testing and Molecular Profiling of Clinical Plasmodium falciparum Isolates from Cambodia from 2008 to 2013 Suggest Emerging Piperaquine Resistance.
Antimicrob Agents Chemother;
59(8): 4631-43, 2015 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26014942
3.
Pharmacokinetics and pharmacodynamics of (+)-primaquine and (-)-primaquine enantiomers in rhesus macaques (Macaca mulatta).
Antimicrob Agents Chemother;
58(12): 7283-91, 2014 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25267666
4.
Randomized, double-blind, placebo-controlled clinical trial of a two-day regimen of dihydroartemisinin-piperaquine for malaria prevention halted for concern over prolonged corrected QT interval.
Antimicrob Agents Chemother;
58(10): 6056-67, 2014 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25092702
5.
Anti-relapse activity of mirincamycin in the Plasmodium cynomolgi sporozoite-infected Rhesus monkey model.
Malar J;
13: 409, 2014 Oct 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25326032
6.
Pharmacokinetic evaluation of intravenous artesunate in adults with uncomplicated falciparum malaria in Kenya: a phase II study.
Malar J;
13: 281, 2014 Jul 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25047305
7.
A simplified intravenous artesunate regimen for severe malaria.
J Infect Dis;
205(2): 312-9, 2012 Jan 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22180622
8.
Pharmacokinetics and pharmacodynamics of oral artesunate monotherapy in patients with uncomplicated Plasmodium falciparum malaria in western Cambodia.
Antimicrob Agents Chemother;
56(11): 5484-93, 2012 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22869581
9.
Optimizing the HRP-2 in vitro malaria drug susceptibility assay using a reference clone to improve comparisons of Plasmodium falciparum field isolates.
Malar J;
11: 325, 2012 Sep 13.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22974086
10.
Absolute bioavailability of cis-mirincamycin and trans-mirincamycin in healthy rhesus monkeys and ex vivo antimalarial activity against Plasmodium falciparum.
Antimicrob Agents Chemother;
55(12): 5881-6, 2011 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21947400
11.
Artemisinin resistance in Cambodia: a clinical trial designed to address an emerging problem in Southeast Asia.
Clin Infect Dis;
51(11): e82-9, 2010 Dec 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21028985
12.
Dose-dependent risk of neutropenia after 7-day courses of artesunate monotherapy in Cambodian patients with acute Plasmodium falciparum malaria.
Clin Infect Dis;
51(12): e105-14, 2010 Dec 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21070142
13.
A simplified liquid chromatography-mass spectrometry assay for artesunate and dihydroartemisinin, its metabolite, in human plasma.
Molecules;
15(12): 8747-68, 2010 Dec 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21124272
14.
Dihydroartemisinin-piperaquine failure associated with a triple mutant including kelch13 C580Y in Cambodia: an observational cohort study.
Lancet Infect Dis;
15(6): 683-91, 2015 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25877962
15.
Population pharmacokinetics of halofantrine in healthy volunteers and patients with symptomatic falciparum malaria.
J Pharm Pharmacol;
64(11): 1603-13, 2012 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23058047
16.
Current status of artemisinin-resistant falciparum malaria in South Asia: a randomized controlled artesunate monotherapy trial in Bangladesh.
PLoS One;
7(12): e52236, 2012.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23272227
17.
Artesunate dose escalation for the treatment of uncomplicated malaria in a region of reported artemisinin resistance: a randomized clinical trial.
PLoS One;
6(5): e19283, 2011.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21603629
18.
Nonisotopic, semiautomated plasmodium falciparum bioassay for measurement of antimalarial drug levels in serum or plasma.
Antimicrob Agents Chemother;
48(11): 4485-7, 2004 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15504891
19.
Plasmodium falciparum-based bioassay for measurement of artemisinin derivatives in plasma or serum.
Antimicrob Agents Chemother;
48(3): 954-60, 2004 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-14982789
20.
Artemether bioavailability after oral or intramuscular administration in uncomplicated falciparum malaria.
Antimicrob Agents Chemother;
47(12): 3795-8, 2003 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-14638485