Detalhe da pesquisa
1.
An Unusual Intramolecular Halogen Bond Guides Conformational Selection.
Angew Chem Int Ed Engl;
57(31): 9970-9975, 2018 07 26.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29873877
2.
Development of Selective Pyrido[2,3-d]pyrimidin-7(8H)-one-Based Mammalian STE20-Like (MST3/4) Kinase Inhibitors.
J Med Chem;
67(5): 3813-3842, 2024 Mar 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38422480
3.
Shifting the selectivity of pyrido[2,3-d]pyrimidin-7(8H)-one inhibitors towards the salt-inducible kinase (SIK) subfamily.
Eur J Med Chem;
254: 115347, 2023 Jun 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37094449
4.
Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3ß Inhibitors.
J Med Chem;
65(2): 1283-1301, 2022 01 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34213342
5.
The Small-Molecule Inhibitor MRIA9 Reveals Novel Insights into the Cell Cycle Roles of SIK2 in Ovarian Cancer Cells.
Cancers (Basel);
13(15)2021 Jul 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34359562
6.
Structure-Based Design of Selective Salt-Inducible Kinase Inhibitors.
J Med Chem;
64(12): 8142-8160, 2021 06 24.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34086472
7.
A Highly Selective Chemical Probe for Activin Receptor-like Kinases ALK4 and ALK5.
ACS Chem Biol;
15(4): 862-870, 2020 04 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32176847
8.
Identification of molecular targets for the targeted treatment of gastric cancer using dasatinib.
Oncotarget;
11(5): 535-549, 2020 Feb 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32082487
9.
Pyridinylimidazoles as dual glycogen synthase kinase 3ß/p38α mitogen-activated protein kinase inhibitors.
Eur J Med Chem;
175: 309-329, 2019 Aug 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31096153
10.
Fast Iterative Synthetic Approach toward Identification of Novel Highly Selective p38 MAP Kinase Inhibitors.
J Med Chem;
62(23): 10757-10782, 2019 12 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31702918
11.
LASSBio-897 Reduces Lung Injury Induced by Silica Particles in Mice: Potential Interaction with the A2A Receptor.
Front Pharmacol;
8: 778, 2017.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29163164
12.
Identification and further development of potent TBK1 inhibitors.
ACS Chem Biol;
10(1): 289-98, 2015 Jan 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25540906
13.
Acylhydrazone derivatives: a patent review.
Expert Opin Ther Pat;
24(11): 1161-70, 2014 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25213630
14.
Novel potent imidazo[1,2-a]pyridine-N-Glycinyl-hydrazone inhibitors of TNF-α production: in vitro and in vivo studies.
PLoS One;
9(3): e91660, 2014.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24632827
15.
Novel 2-chloro-4-anilino-quinazoline derivatives as EGFR and VEGFR-2 dual inhibitors.
Eur J Med Chem;
71: 1-14, 2014 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24269511
16.
N-acylhydrazone derivative ameliorates monocrotaline-induced pulmonary hypertension through the modulation of adenosine AA2R activity.
Int J Cardiol;
173(2): 154-62, 2014 May 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24630383
17.
Beneficial effects of a novel agonist of the adenosine A2A receptor on monocrotaline-induced pulmonary hypertension in rats.
Br J Pharmacol;
169(5): 953-62, 2013 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23530610
18.
Phenylpiperazine derivatives: a patent review (2006 - present).
Expert Opin Ther Pat;
22(10): 1169-78, 2012 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22957817
19.
Antihypertensive profile of 2-thienyl-3,4-methylenedioxybenzoylhydrazone is mediated by activation of the A2A adenosine receptor.
Eur J Med Chem;
55: 49-57, 2012 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22857782
20.
LASSBio-897 Reduces Lung Injury Induced by Silica Particles in Mice: Potential Interaction with the A2AReceptor
Artigo
em Inglês
| Arca: Repositório institucional da Fiocruz
| ID: arc-24883