Detalhe da pesquisa
1.
Effect of a Recombinant Human Soluble Thrombomodulin on Mortality in Patients With Sepsis-Associated Coagulopathy: The SCARLET Randomized Clinical Trial.
JAMA;
321(20): 1993-2002, 2019 05 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31104069
2.
Evaluation of drug-drug interaction between the novel cPLA2 inhibitor AK106-001616 and methotrexate in rheumatoid arthritis patients.
Xenobiotica;
45(7): 615-24, 2015.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25579091
3.
A randomized, double-blind, placebo-controlled, Phase 2b study to evaluate the safety and efficacy of recombinant human soluble thrombomodulin, ART-123, in patients with sepsis and suspected disseminated intravascular coagulation.
Crit Care Med;
41(9): 2069-79, 2013 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23979365
4.
Pharmacological Differentiation of Thrombomodulin Alfa and Activated Protein C on Coagulation and Fibrinolysis In Vitro.
Clin Appl Thromb Hemost;
24(6): 859-866, 2018 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29683037
5.
Population pharmacokinetic analysis of thrombomodulin alfa to support dosing rationale in patients with renal impairment.
Clin Pharmacol Drug Dev;
4(3): 210-7, 2015.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27140801
6.
Dysregulation of inflammatory and hemostatic markers in sepsis and suspected disseminated intravascular coagulation.
Clin Appl Thromb Hemost;
21(2): 120-7, 2015 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24254894
7.
Thrombin generation mediators and markers in sepsis-associated coagulopathy and their modulation by recombinant thrombomodulin.
Clin Appl Thromb Hemost;
20(2): 129-35, 2014 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23804232
8.
Model-based analysis of covariate effects on population pharmacokinetics of thrombomodulin alfa in patients with disseminated intravascular coagulation and normal subjects.
J Clin Pharmacol;
51(9): 1276-85, 2011 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21098690
9.
Photo-electrochemical degradation of some chlorinated organic compounds on n-TiO2 electrode.
Chemosphere;
73(8): 1279-83, 2008 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18718634