Detalhe da pesquisa
1.
Novel RNA molecular bioengineering technology efficiently produces functional miRNA agents.
RNA;
30(6): 680-694, 2024 May 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38429100
2.
RNA Drugs and RNA Targets for Small Molecules: Principles, Progress, and Challenges.
Pharmacol Rev;
72(4): 862-898, 2020 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32929000
3.
A Novel Integrated Pharmacokinetic-Pharmacodynamic Model to Evaluate Combination Therapy and Determine In Vivo Synergism.
J Pharmacol Exp Ther;
377(3): 305-315, 2021 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33712506
4.
MicroRNA-1291-5p Sensitizes Pancreatic Carcinoma Cells to Arginine Deprivation and Chemotherapy through the Regulation of Arginolysis and Glycolysis.
Mol Pharmacol;
98(6): 686-694, 2020 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33051382
5.
Pharmacokinetic and Pharmacodynamic Factors Contribute to Synergism between Let-7c-5p and 5-Fluorouracil in Inhibiting Hepatocellular Carcinoma Cell Viability.
Drug Metab Dispos;
48(12): 1257-1263, 2020 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33051247
6.
Novel approaches for efficient in vivo fermentation production of noncoding RNAs.
Appl Microbiol Biotechnol;
104(5): 1927-1937, 2020 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31953559
7.
Bioengineering of a single long noncoding RNA molecule that carries multiple small RNAs.
Appl Microbiol Biotechnol;
103(15): 6107-6117, 2019 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31187211
8.
Bioengineered Noncoding RNAs Selectively Change Cellular miRNome Profiles for Cancer Therapy.
J Pharmacol Exp Ther;
365(3): 494-506, 2018 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29602831
9.
Bioengineered NRF2-siRNA Is Effective to Interfere with NRF2 Pathways and Improve Chemosensitivity of Human Cancer Cells.
Drug Metab Dispos;
46(1): 2-10, 2018 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29061583
10.
MicroRNA Pharmacoepigenetics: Posttranscriptional Regulation Mechanisms behind Variable Drug Disposition and Strategy to Develop More Effective Therapy.
Drug Metab Dispos;
44(3): 308-19, 2016 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26566807
11.
Chimeric MicroRNA-1291 Biosynthesized Efficiently in Escherichia coli Is Effective to Reduce Target Gene Expression in Human Carcinoma Cells and Improve Chemosensitivity.
Drug Metab Dispos;
43(7): 1129-36, 2015 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25934574
12.
[Establishment of MDCK cell models expressing human MATE1 or co-expressing with human OCT1 or OCT2].
Yao Xue Xue Bao;
50(7): 842-7, 2015 Jul.
Artigo
em Zh
| MEDLINE
| ID: mdl-26552145
13.
[In vitro interaction of deferiprone with cellular membrane transporters of hOCTs and hOAT1].
Zhejiang Da Xue Xue Bao Yi Xue Ban;
43(2): 129-34, 2014 03.
Artigo
em Zh
| MEDLINE
| ID: mdl-24782365
14.
Molecular Engineering of Functional SiRNA Agents.
ACS Synth Biol;
2024 May 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38733599
15.
Recent Advances in Novel Recombinant RNAs for Studying Post-transcriptional Gene Regulation in Drug Metabolism and Disposition.
Curr Drug Metab;
24(3): 175-189, 2023.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37170982
16.
Erratum: Author correction to 'Bioengineered miR-124-3p prodrug selectively alters the proteome of human carcinoma cells to control multiple cellular components and lung metastasis in vivo' [Acta Pharmaceutica Sinica B 11 (2021) 3950-3965].
Acta Pharm Sin B;
13(8): 3577-3578, 2023 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37655312
17.
ATR Inhibition in Advanced Urothelial Carcinoma.
Clin Genitourin Cancer;
21(2): 203-207, 2023 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36604210
18.
Use of recombinant microRNAs as antimetabolites to inhibit human non-small cell lung cancer.
Acta Pharm Sin B;
13(10): 4273-4290, 2023 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37799388
19.
Deliver the promise: RNAs as a new class of molecular entities for therapy and vaccination.
Pharmacol Ther;
230: 107967, 2022 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34403681
20.
Bioengineered miR-34a modulates mitochondrial inner membrane protein 17 like 2 (MPV17L2) expression toward the control of cancer cell mitochondrial functions.
Bioengineered;
13(5): 12489-12503, 2022 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35579419