Detalhe da pesquisa
1.
Human colorectal cancer: upregulation of the adaptor protein Rai in TILs leads to cell dysfunction by sustaining GSK-3 activation and PD-1 expression.
Cancer Immunol Immunother;
73(1): 2, 2024 Jan 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38175205
2.
Molecular Signature of Monocytes Shaped by the Shigella sonnei 1790-Generalized Modules for Membrane Antigens Vaccine.
Int J Mol Sci;
25(2)2024 Jan 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38256189
3.
Enhanced IL-9 secretion by p66Shc-deficient CLL cells modulates the chemokine landscape of the stromal microenvironment.
Blood;
137(16): 2182-2195, 2021 04 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33181836
4.
A novel class of oxazepine-based anti-cancer agents induces cell death in primary human CLL cells and efficiently reduces tumor growth in Eµ-TCL1 mice through the JNK/STAT4/p66Shc axis.
Pharmacol Res;
174: 105965, 2021 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34732370
5.
Differential Proteomic Analysis of Astrocytes and Astrocytes-Derived Extracellular Vesicles from Control and Rai Knockout Mice: Insights into the Mechanisms of Neuroprotection.
Int J Mol Sci;
22(15)2021 Jul 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34360699
6.
The Shc protein Rai enhances T-cell survival under hypoxia.
J Cell Physiol;
235(11): 8058-8070, 2020 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31944299
7.
p66Shc deficiency in the Eµ-TCL1 mouse model of chronic lymphocytic leukemia enhances leukemogenesis by altering the chemokine receptor landscape.
Haematologica;
104(10): 2040-2052, 2019 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30819907
8.
The Adaptor Protein Rai/ShcC Promotes Astrocyte-Dependent Inflammation during Experimental Autoimmune Encephalomyelitis.
J Immunol;
197(2): 480-90, 2016 07 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27288534
9.
Severe Reduction in Number and Function of Peripheral T Cells Does Not Afford Protection toward Emphysema and Bronchial Remodeling Induced in Mice by Cigarette Smoke.
Am J Pathol;
186(7): 1814-1824, 2016 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27157991
10.
Regulation of T Cell Activation and Differentiation by Extracellular Vesicles and Their Pathogenic Role in Systemic Lupus Erythematosus and Multiple Sclerosis.
Molecules;
22(2)2017 Feb 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28157168
11.
Ligation of human Fc receptor like-2 by monoclonal antibodies down-regulates B-cell receptor-mediated signalling.
Immunology;
143(3): 341-53, 2014 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24797767
12.
Statins: from cholesterol-lowering drugs to novel immunomodulators for the treatment of Th17-mediated autoimmune diseases.
Pharmacol Res;
88: 41-52, 2014 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24657239
13.
CSF-1R in Cancer: More than a Myeloid Cell Receptor.
Cancers (Basel);
16(2)2024 Jan 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38254773
14.
Leukemic cell-secreted interleukin-9 suppresses cytotoxic T cell-mediated killing in chronic lymphocytic leukemia.
Cell Death Dis;
15(2): 144, 2024 Feb 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38360867
15.
p66Shc is a negative regulator of FcεRI-dependent signaling in mast cells.
J Immunol;
186(9): 5095-106, 2011 May 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21430228
16.
Correction: The Adaptor Protein Rai/ShcC Promotes Astrocyte-Dependent Inflammation during Experimental Autoimmune Encephalomyelitis.
J Immunol;
197(10): 4178, 2016 11 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27815449
17.
Dissecting in Vitro the Activation of Human Immune Response Induced by Shigella sonnei GMMA.
Front Cell Infect Microbiol;
12: 767153, 2022.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35186786
18.
Design and synthesis of multifunctional microtubule targeting agents endowed with dual pro-apoptotic and anti-autophagic efficacy.
Eur J Med Chem;
235: 114274, 2022 May 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35344902
19.
Rai acts as a negative regulator of autoimmunity by inhibiting antigen receptor signaling and lymphocyte activation.
J Immunol;
182(1): 301-8, 2009 Jan 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19109161
20.
Novel quinolone-based potent and selective HDAC6 inhibitors: Synthesis, molecular modeling studies and biological investigation.
Eur J Med Chem;
212: 112998, 2021 Feb 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33199154