Detalhe da pesquisa
1.
Computational design of soluble and functional membrane protein analogues.
Nature;
2024 Jun 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38898281
2.
Structural basis for Clostridium perfringens enterotoxin targeting of claudins at tight junctions in mammalian gut.
Proc Natl Acad Sci U S A;
118(15)2021 04 13.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33876770
3.
Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes.
J Biol Chem;
298(9): 102357, 2022 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35952760
4.
Highlighting membrane protein structure and function: A celebration of the Protein Data Bank.
J Biol Chem;
296: 100557, 2021.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33744283
5.
Claudin-9 structures reveal mechanism for toxin-induced gut barrier breakdown.
Proc Natl Acad Sci U S A;
116(36): 17817-17824, 2019 09 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31434788
6.
Crystal Structure of Aspirin-Acetylated Human Cyclooxygenase-2: Insight into the Formation of Products with Reversed Stereochemistry.
Biochemistry;
55(8): 1226-38, 2016 Mar 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26859324
7.
Structural and biophysical insights into targeting of claudin-4 by a synthetic antibody fragment.
Commun Biol;
7(1): 733, 2024 Jun 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38886509
8.
Computational design of soluble functional analogues of integral membrane proteins.
bioRxiv;
2024 Mar 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38496615
9.
Investigating substrate promiscuity in cyclooxygenase-2: the role of Arg-120 and residues lining the hydrophobic groove.
J Biol Chem;
287(29): 24619-30, 2012 Jul 13.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22637474
10.
Structural Basis of Clostridium perfringens Enterotoxin Activation and Oligomerization by Trypsin.
Toxins (Basel);
15(11)2023 10 31.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37999500
11.
Cryo-EM structures of a synthetic antibody against 22 kDa claudin-4 reveal its complex with Clostridium perfringens enterotoxin.
bioRxiv;
2023 Jun 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37398044
12.
Claudin-1 interacts with EPHA2 to promote cancer stemness and chemoresistance in colorectal cancer.
Cancer Lett;
579: 216479, 2023 11 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37924938
13.
The structural basis of endocannabinoid oxygenation by cyclooxygenase-2.
J Biol Chem;
286(23): 20736-45, 2011 Jun 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21489986
14.
Human cyclooxygenase-2 is a sequence homodimer that functions as a conformational heterodimer.
J Biol Chem;
286(21): 19035-46, 2011 May 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21467029
15.
Disruption of Claudin-Made Tight Junction Barriers by Clostridium perfringens Enterotoxin: Insights from Structural Biology.
Cells;
11(5)2022 03 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35269525
16.
The structure of NS-398 bound to cyclooxygenase-2.
J Struct Biol;
176(2): 254-8, 2011 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21843643
17.
Structural basis of fatty acid substrate binding to cyclooxygenase-2.
J Biol Chem;
285(29): 22152-63, 2010 Jul 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20463020
18.
High-Throughput Nano-Scale Characterization of Membrane Proteins Using Fluorescence-Detection Size-Exclusion Chromatography.
Methods Mol Biol;
2025: 361-388, 2019.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31267462