Prothrombin time predicts steroid response in severe alcohol-related hepatitis.

BACKGROUND AND AIMS: Alcohol-related hepatitis (AH) is the most severe form of acute alcohol-related liver disease. Maddrey's discriminant function ≥32 defines the severe form of AH, which is associated with a high mortality. Steroid therapy represents the main medical treatment that may reduce short-term mortality. Lille score at day 7 assesses the therapeutic response to steroid therapy. At present, no parameters able to predict the response to steroid therapy have been highlighted. The aim of the present study was to evaluate if baseline prothrombin time (BPT) could predict the response to steroid in severe AH (sAH). METHODS: Patients consecutively admitted in two Italian Liver Units, from 2017 to 2022, suffering from sAH were included. Data were collected prospectively. In order to evaluate if BPT could predict steroid response, we assessed the correlation between BPT using the Lille score at day 7. RESULTS: A total of 52 patients received steroid treatment were enrolled in the study. The response to therapy was assessed by Lille score at day 7. Responders were 34 patients (65%), non-responders 18 patients (34%). BPT significantly predicted the steroid response (p < .001). The likelihood of not responding to the steroid therapy was significantly higher in patients with higher BPT (OR = 2.954). CONCLUSIONS: BPT value predicted steroid response in patients with sAH. BPT could quickly identify non-responder patients to steroid therapy, reducing the risk of infections and it could allow the early evaluation for liver transplantation.

Latent change scores models for applied research: A practical guide using Mplus.

The present article provides a practical guide for modelling and interpreting several basic applications of the latent change scores (LCS) model, a useful and flexible approach for the analysis of change. The article is addressed to students, researchers and practitioners who are familiar with structural equation modelling but new to LCS. We first provided a gentle introduction to the LCS model using non-technical language and minimal mathematical formalism. We illustrated the basic ideas behind this approach, introducing LCS in its simplest form. We show how this model can be straightforwardly extended to more complex applications, including the dual change score (DCS) model and some of its variants (i.e., the proportional change and the constant change models). We illustrated how the univariate LCS model can be used to determine the growth trajectory of a variable across multiple waves of assessment. Next, we focused on the bivariate case, which allows for the modelling of the dynamic relations between two variables. For each model, we provided easy-to-follow examples of applications based on Schwartz's theory of basic personal values. The examples are accompanied by annotated syntax and output showing how they can be implemented with the Mplus software and how results can be interpreted.

Signs of Dissociation and Symptoms of Post-Traumatic Stress Disorder in Inflammatory Bowel Disease: A Case-Control Study.

BACKGROUND: Several psychological disorders have been described in patients affected by inflammatory bowel disease (IBD). Few studies have focused on the relationship between IBD and post-traumatic stress disorder (PTSD) symptoms, and no data are available on the relationship between IBD and dissociative symptoms. The aim of the present study was to evaluate the prevalence of PTSD and dissociative symptoms in a sample of IBD patients compared to healthy controls. A possible relationship with disease activity was also investigated. METHODS: A total of 112 IBD patients, 55 Crohn's disease (CD) and 57 ulcerative colitis (UC), and 114 healthy individuals were evaluated. IBD patients were divided into 3 subgroups according to disease activity (remission, mild, and moderate). The revised version of the Impact of Event Scale (IES-R) and the Dissociative Experience Scale (DES) were administered to patients and controls. RESULTS: IBD patients showed significantly higher rates of PTSD and dissociative symptoms compared to healthy controls. No differences were found between CD and UC patients. PTSD and dissociative symptoms were higher among CD patients with mild to moderate-severe activity compared to the remission group. No differences were found among UC patients with different activity levels. CONCLUSION: IBD patients show a high prevalence of dissociative and traumatic affective disorders. Future studies are needed to investigate the role of these disorders in the clinical course and management of IBD patients according to the different disease activity phase.

Development and Validation of a Short Version of the Reinforcement Sensitivity Theory of Personality Questionnaire (RST-PQ-S).

We conducted three studies (total n = 998) aimed at developing and validating a shortened version of the Reinforcement Sensitivity Theory of Personality Questionnaire (i.e., the RST-PQ-S). In Study 1 (n = 341), twenty-two items were selected from the original RST-PQ, based on both theoretical and empirical criteria. Confirmatory factor analysis (CFA) on this short-form supported the six-factor structure comprising: FFFS, BIS, and four BAS components (Reward Interest, Goal Drive-Persistence, Reward Reactivity, and Impulsivity). The six scale scores showed adequate levels of internal consistency. Construct validity was supported by correlations with established personality measures. In Study 2 (n = 340), CFA results were cross-validated in an independent sample and construct validity was supported by correlations with BIS/BAS scales. In Study 3 (n = 317) test-retest correlations showed acceptable-to-good levels of temporal stability over a four-week interval. Results revealed a substantial overlap with original, full-length RST-PQ, providing evidence for the comparability of the two versions. Latent State-Trait analyses showed that the items of the RST-PQ-S mostly capture interindividual differences that are stable across situations. Taken together, findings indicate that the RST-PQ-S provides an efficient, valid and reliable alterative to the longer RST-PQ.

BIS and BAS Sensitivities at Different Levels of Personality Description: A Latent-Variable Approach with Self- and Informant-Ratings.

We examine the structural overlap of the Behavioral Inhibition System (BIS) and the Behavioral Approach System (BAS) with Stability and Plasticity, the two higher-order factors encompassing the Big Five. Carver and White's BIS/BAS and the Big Five Inventory were administered to a sample of 330 adults, serving both as targets and informants. Self- and other-ratings were modeled by using the Correlated Trait-Correlated Method model. BIS and BAS correlated highly with metatraits, after method variance and measurement error were partialled out: BIS was positively related to Stability, while BAS was positively related to Plasticity and negatively related to Stability. After the higher-order factors were controlled, the BIS was highly and positively related to Emotional stability, whereas the BAS had a small but significant relationship with Extraversion. Findings are discussed with regard to the most appropriate level of generality/specificity at which the personality correlates of BIS and BAS can be investigated.

Personality trait change at work: Associations with organizational socialization and identification.

OBJECTIVE: This study investigates associations between Big Five personality trait change, organizational socialization, and organizational identification during a 3-year police officer training program (N = 416 police officer cadets). METHOD: Participants completed a questionnaire measuring the Big Five personality traits when they entered the training academy, and then, completed the same personality questionnaire, along with measures of organizational socialization and identification, during their 2nd (n = 360) and 3rd (n = 397) year of training. RESULTS: Results corroborated the hypotheses that (a) the Big Five traits can show systematic changes even across a relatively short time period and (b) this change is functional, given that the latent difference scores of all Big Five traits significantly predicted increases in organizational socialization and identification. CONCLUSION: The Big five personality traits showed significant mean level changes across the 3-year training program. Although these changes were not fully consistent with theoretical expectations, they did predict two aspects of organizational adjustment (socialization and identification). The theoretical and practical implications of these findings were discussed.

Stability and change of basic personal values in early adolescence: A 2-year longitudinal study.

OBJECTIVE: We examined patterns of change and stability in the whole set of 10 Schwartz values over 2 years during early adolescence. METHOD: Participants completed the Portrait Values Questionnaire repeatedly throughout the junior high school years. The study involved six waves of data and a total of 382 respondents aged 10 years at the first measurement occasion (43% female). We investigated multiple types of stability in the values: mean-level, rank-order, and ipsative stability. RESULTS: At the mean-level, self-enhancement, and Openness to change values increased in importance. Self-direction and hedonism values showed the greatest increase-about one-third of a standard deviation. Conservation and self-transcendence values did not change with the exception of tradition, which decreased slightly. After correcting for measurement error, rank-order stability coefficients ranged from .39 (hedonism) to .77 (power). Correlations between value hierarchies measured 2 years apart were ≥.85 for 75% of respondents, and ≤.12 for 5% of the respondents. Thus only a small proportion of participants experienced a marked change in the relative importance they ascribed to the 10 values. CONCLUSIONS: Results are discussed and related to earlier findings on patterns and magnitude of value change during other periods of the life span.

A look into the relationship between personality traits and basic values: A longitudinal investigation.

OBJECTIVE: The present study examines the longitudinal association between basic personal values and the Big Five personality traits. METHOD: A sample of 546 young adults (57% females) with a mean age of 21.68 years (SD = 1.60) completed the Portrait Values Questionnaire and the Big Five Questionnaire at three time points, each separated by an interval of 4 years. Cross-lagged models were used to investigate the possible reciprocal relations between traits and values, after the stability of the variables was taken into account. RESULTS: We found that values did not affect trait development. Traits, by contrast, have some effects on how values change. Specifically, high levels of Agreeableness predict an increase over time in the importance assigned to benevolence values. Similarly, high levels of Openness predict a later increase in the importance assigned to self-direction values. The same effect was not found for the other traits. Additionally, except for in the case of Emotional Stability, traits showed synchronous (i.e., within wave) correlations with values, suggesting that part of this relationship is due to common antecedents. CONCLUSIONS: Mechanisms underlying the associations between traits and values are discussed.

Gender differences in personal values of national and local Italian politicians, activists and voters.

Theorists of politics of presence postulate that women elected to political office would still hold values similar to ordinary women and therefore represent them better than male politicians. Gender differences in personal values, which underline and give coherence to core political values, have been found among voters: males score higher on self-enhancement values (power and achievement) and females higher on self-transcendence values (universalism and benevolence). Our study aims to explore if gender differences in personal values are still present among activists, local and national politicians. We administer a shortened version of the Portrait Values Questionnaire to 233 Italian national politicians (46% females), 425 local politicians (56% females), 626 political activists (44% females), and 3249 ordinary citizens (49% females). Our results confirm only partially politics of presence theory: females at all levels of political involvement score higher in self-transcendent values that emphasise concern for the welfare of others, but no significant gender differences emerge for self-enhancement, which favour the pursuit of self-interest. Our findings support ethical struggles for more balanced gender representation: a higher proportion of women in politics could strengthen the political representation of self-transcendence values.

Ego-resiliency development from late adolescence to emerging adulthood: A ten-year longitudinal study.

This study examined the development of ego-resiliency from late adolescence to emerging adulthood, using a 10-year cohort-sequential design. Participants were 335 Italian adolescents (173 females and 162 males), living, at the time of the study, in Genzano, a small city near to Rome. Latent growth curve analyses indicated that the developmental trajectory of ego-resiliency from 15 to 25 years is adequately described by a piecewise model that included separate growth profiles corresponding to different developmental stages. Essentially, ego-resiliency remained remarkably stable until the end of high school, and then encountered a phase of relative increase. Moreover, the trajectory of ego-resiliency from ages 15 to 19 was predicted by self-efficacy beliefs in managing negative emotions, and the trajectory from age 19 to 25 was predicted by experienced familial support and self-efficacy beliefs in expressing positive emotions at age 15. Experienced stressful life events also accounted for individuals' deviation from the typical ego-resiliency trajectory.

Reciprocal Relations Between Emotional Self-Efficacy Beliefs and Ego-Resiliency Across Time.

The present study examined the longitudinal relations of adolescents' self-reported ego-resiliency to their emotional self-efficacy beliefs in expressing positive emotions and in managing negative emotions as they moved into early adulthood. Participants were 239 females and 211 males with a mean age of 17 years (SD = .80) at T1, 19 years (SD = .80) at T2, 21 years (SD = .82) at T3, and 25 years (SD = .80) at T4. A four-wave cross-lagged regression model and mediational analyses were used. In a panel structural equation model controlling for the stability of the constructs, reciprocal relationships across time were found between ego-resiliency and emotional self-efficacy beliefs related to the expression of positive emotions and to the management of negative emotions. Moreover, the relation between ego-resiliency assessed at T1 and T3, and ego-resiliency assessed at T2 and T4, was mediated through emotional self-efficacy beliefs (at T2 and T3, respectively), and vice versa. The posited conceptual model accounted for a significant portion of variance in ego-resiliency and has implications for understanding the development of ego-resiliency.

Egoistic and moralistic self-enhancement in the eye of the beholder: a cross-informant study.

This study was conceived to assess the agreement between self- and other reports of egoistic (E) and moralistic (M) self-enhancement (SE). A self-report scale assessing E-SE and M-SE was filled out by 304 participants (mean age = 39.11, SD = 10.12, 54% female). The scale, with items worded in third person, was also completed by 304 informants (one for each target participant). Data were subjected to a correlated-traits correlated-methods model. Confirmatory factor analysis yielded two distinct factors for both self- and other ratings of E-SE and M-SE. A significant correlation across raters was observed for each factor. Proportion of trait variance was .58 for E-SE and .35 for M-SE. Proportion of method variance was .24 and .41, respectively. E-SE and M-SE were substantially correlated within each data source. However, the two measures became orthogonal after method variance was partialed out. Measures of E-SE and M-SE include both trait and artifactual components of variance, which are likely to reflect individual differences in the style of self-presentation and response bias (i.e., tendencies to exaggerate agentic and communal qualities). The trait components of E-SE and M-SE represent two unrelated tendencies that can be captured and distinguished not only through self-judgments, but also by an external observer.

On the cross-cultural replicability of the resilient, undercontrolled, and overcontrolled personality types.

Personality types reflect typical configurations of personality attributes within individuals. Over the last 20 years, researchers have identified a set of three replicable personality types: resilient (R), undercontrolled (U), and overcontrolled (O) types. In this study, we examined the cross-cultural replicability of the RUO types in Italy, Poland, Spain, and the United States. Personality types were identified using cluster analyses of Big Five profiles in large samples of college students from Italy (n = 322), the United States (n = 499), Spain (n = 420), and Poland (n = 235). Prior to clustering the profiles, the measurement invariance of the Big Five measure across samples was tested. We found evidence for the RUO types in all four samples. The three-cluster solution showed a better fit over alternative solutions and had a relatively high degree of cross-cultural generalizability. The RUO types are evident in samples from four countries with distinct linguistic and cultural traditions. Results were discussed in light of the importance of considering how traits are organized within individuals for advancing contemporary personality psychology.

Self-efficacy, perceptions of context, and burnout: a multilevel study on nurses.

BACKGROUND: The role of personal and situational factors in burnout development in the hospital context is well known. The majority of studies used standardized and generic scales and focused exclusively on the individual level of analysis, underestimating the role of teamwork effects. OBJECTIVES: This study adopted a contextualized and multilevel approach in order to examine the different roles of individual and unit level nurse efficacy beliefs and hospital perceptions of context in predicting job burnout. METHODS: Nurses (N=1020) belonging to 118 units completed two measures specifically tailored for the nursing environment: nurse self-efficacy, perceptions of context (teamwork, supervisor, management, and workload) together with MBI-GS exhaustion and cynicism scales. Multilevel confirmatory factor analysis was performed in order to verify the internal validity of nurse self-efficacy and hospital perceptions of context scales. A multilevel structural equation model was tested at individual and unit levels, using nurse self-efficacy, hospital perceptions of context and age as predictors of exhaustion and cynicism. RESULTS: The good psychometric properties of the scales were confirmed. At individual level, nurse self-efficacy was the strongest predictor of both burnout dimensions. Exhaustion was also predicted by perception of workload and perception of management, while cynicism was also predicted by perceptions of teamwork, workload, and age. At unit level, perceptions of workload and teamwork emerged as predictors of unit exhaustion and cynicism, respectively. CONCLUSIONS: Based on our results, it is possible to plan distinct individual and/or unit-focused interventions in order to prevent hospital staff burnout.

Alpha and Beta traits and egoistic and moralistic self-enhancement: a point of convergence between two research traditions.

OBJECTIVE: The current study investigated the relationship of egoistic and moralistic self-enhancement with Alpha and Beta, the two higher-order factors of personality encompassing the Big Five. METHOD: Four hundred sixteen Italian adults (59% females, mean age = 41.13) completed self-report measures of the Big Five and of egoistic and moralistic self-enhancement. They were also rated by acquaintances on the two self-enhancement measures. A cross-observer design within the framework of structural equation modeling was used to disentangle the variance shared by the constructs that is due to (a) substantive personality characteristics (i.e., the variance of egoistic and moralistic self-enhancement common to different informants), (b) response bias (i.e., the tendency to exaggerate agentic and communal qualities), and (c) halo effect (i.e., the common factor underlying all self-report measures). RESULTS: Findings revealed significant correlations between Alpha and Beta and the substantive parts of egoistic and moralistic dimensions. Beta was primarily related to egoistic self-enhancement, whereas alpha was mostly related to moralistic self-enhancement. Nevertheless, a substantial portion of variance in Alpha and Beta was explained by response bias and halo effect. CONCLUSIONS: Substance, bias, and method variance all represent important sources of covariation among the Big Five.

A longitudinal investigation of egoistic and moralistic self-enhancement.

This study used a 3-wave longitudinal design to investigate stability and change of egoistic and moralistic self-enhancement. Participants (n = 195) were followed for 6 years, from late adolescence (age 15) to emerging adulthood (age 21). A significant degree of rank-order stability was found that reveals a reasonable continuity in the individuals' relative standing on measures of egoistic and moralistic self-enhancement. Latent growth curve analysis was used to track the developmental trajectories of the examined constructs. Findings revealed that egoistic self-enhancement is stable from 15 to 21 years, whereas moralistic self-enhancement slightly decreases during the same developmental period. Cross-lagged models were used to examine the reciprocal relations between self-enhancement and the Big Five personality traits. No prospective effects were found between the constructs, which develop independently from late adolescence to young adulthood, showing only synchronous associations. Implications for personality research and assessment are discussed.

Prospective associations between grandiose narcissism and perfectionism: A longitudinal study in adolescence.

The current study investigates the longitudinal association between grandiose narcissism and multidimensional perfectionism over 2 years in adolescence. We adopted the Narcissistic Admiration and Rivalry Concept, which differentiates between two aspects of grandiose narcissism. We also considered multiple dimensions of perfectionism, including Socially Prescribed Perfectionism (SPP) and two forms of Self-Oriented Perfectionism (SOP), namely the tendencies to set high standards of performance (SOP-Striving) and to engage in overly critical self-evaluations (SOP-Critical). The study was conducted in a sample of Italian high school students (n = 331). Concurrent correlations indicated that Admiration was positively related to SOP-Striving and, to a lesser extent, to SOP-Critical and SPP. Rivalry was also positively related to the three perfectionistic dimensions, although correlations were smaller in size than those found for Admiration. Prospective associations between narcissism and perfectionism were analysed using a Random-Intercept Cross-Lagged Panel Model. Results showed that the predominant direction of effects was from narcissism to perfectionism, particularly from Admiration to SOP-Striving and SPP. Findings were discussed in terms of their implications for the understanding of the narcissism-perfectionism link.

Basic personal values in the midst of the COVID-19 pandemic in Italy: A two-wave longitudinal study.

This study investigated value change during two phases of the COVID-19 pandemic in Italy, one of the most affected countries in the world. The first wave of data was collected in summer 2020, when the virus was on the retreat. The second wave was collected in autumn, at the peak of the second pandemic wave (November 2020). We investigated how Schwartz's higher-order values changed over the two waves of the study, using economic condition as a predictor of change. We also examined whether value change predicted subsequent value-expressive behavior. Results showed no mean-level change for self-enhancement, self-transcendence, conservation, and openness to change values, but significant interindividual differences in the amount of change for each of the four values. Economic condition emerged as a significant predictor of change in conservation values: Individuals with a decreasing income since the beginning of the pandemic were more likely to increase the importance assigned to these values with respect to individuals whose economic well-being has remained unchanged. Moreover, an increase in conservation and openness to change values predicted behaviors that are mostly expressive of these values, above and beyond value importance at Time 1. Results and their implications for the study of values are discussed.

Personal values and academic achievement.

Using data from two studies, we investigate the role of basic values in predicting academic achievement. We focus on self-direction and conformity, two-value domains that have been neglected or understudied in earlier research on academic success. In line with the refined value theory, we split self-direction into independence of thought and of action, and conformity into compliance with rules and formal obligations (Rules), and avoidance of upsetting others (Interpersonal). We obtained grades as measures of academic achievement in two samples of Italian high-school students. In Study 1 (n = 234), we measured values with the PVQ-40 and academic motivation. In Study 2 (n = 215), we measured values with the PVQ-RR and both attendance rates and classroom conduct. Results: Both self-direction-thought and conformity-rules correlated with higher grades. These two values related to grades through a different path. Self-direction thought promoted grades through autonomous forms of academic motivation. Conformity rules promoted grades through better teachers' evaluations of students' classroom behaviour. Self-direction-action and conformity-interpersonal were unrelated to grades. Regarding the other values, hedonism and stimulation related negatively to grades. Theoretical and practical implications of results are discussed.

How Is Working Memory Related to Reading Comprehension in Italian Monolingual and Bilingual Children?

This study explored how working memory resources contributed to reading comprehension using tasks that focused on maintenance of verbal information in the phonological store, the interaction between the central executive and the phonological store (WMI), and the storage of bound semantic content in the episodic buffer (immediate narrative memory). We analysed how performance in these tasks was related to text decoding (reading speed and accuracy), listening and reading comprehension. The participants were 62 monolingual and 36 bilingual children (mean age nine years, SD = 9 months) enrolled in the same Italian primary school. Bilingual children were born to immigrant parents and had a long history of exposure to Italian as a second language. The regression analyses showed that reading accuracy and listening comprehension were associated with reading comprehension for monolingual and bilingual children. Two working memory components-WMI and immediate narrative memory-exhibited indirect effects on reading comprehension through reading accuracy and listening comprehension, respectively. Such effects occurred only for monolingual children. We discuss the implications of such findings for text reading and comprehension in monolinguals and bilinguals.