Detalhe da pesquisa
1.
Small Molecules Co-targeting CKIα and the Transcriptional Kinases CDK7/9 Control AML in Preclinical Models.
Cell;
175(1): 171-185.e25, 2018 09 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30146162
2.
The gut microbiome switches mutant p53 from tumour-suppressive to oncogenic.
Nature;
586(7827): 133-138, 2020 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32728212
3.
Cyanide does more to inhibit heme enzymes, than merely serving as an active-site ligand.
Biochem Biophys Res Commun;
455(3-4): 190-3, 2014 Dec 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25449264
4.
Tissue-Predisposition to Cancer Driver Mutations.
Cells;
13(2)2024 01 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38247798
5.
Putative homeostatic role of cancer driver mutations.
Trends Cell Biol;
32(1): 8-17, 2022 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34373150
6.
Functioning of drug-metabolizing microsomal cytochrome P450s: In silico probing of proteins suggests that the distal heme 'active site' pocket plays a relatively 'passive role' in some enzyme-substrate interactions.
In Silico Pharmacol;
4(1): 2, 2016 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26894412
7.
Functioning of Microsomal Cytochrome P450s: Murburn Concept Explains the Metabolism of Xenobiotics in Hepatocytes.
Front Pharmacol;
7: 161, 2016.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27445805
8.
Atypical profiles and modulations of heme-enzymes catalyzed outcomes by low amounts of diverse additives suggest diffusible radicals' obligatory involvement in such redox reactions.
Biochimie;
125: 91-111, 2016 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26969799