Detalhe da pesquisa
1.
Efficient and error-free fluorescent gene tagging in human organoids without double-strand DNA cleavage.
PLoS Biol;
20(1): e3001527, 2022 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35089911
2.
Liver Colonization by Colorectal Cancer Metastases Requires YAP-Controlled Plasticity at the Micrometastatic Stage.
Cancer Res;
82(10): 1953-1968, 2022 05 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35570706
3.
Quantifying single-cell ERK dynamics in colorectal cancer organoids reveals EGFR as an amplifier of oncogenic MAPK pathway signalling.
Nat Cell Biol;
23(4): 377-390, 2021 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33795873
4.
Diverse BRAF Gene Fusions Confer Resistance to EGFR-Targeted Therapy via Differential Modulation of BRAF Activity.
Mol Cancer Res;
18(4): 537-548, 2020 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31911540
5.
Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids.
Nat Genet;
51(5): 824-834, 2019 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31036964
6.
Specific Labeling of Stem Cell Activity in Human Colorectal Organoids Using an ASCL2-Responsive Minigene.
Cell Rep;
22(6): 1600-1614, 2018 02 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29425513
7.
Baculoviral delivery of CRISPR/Cas9 facilitates efficient genome editing in human cells.
PLoS One;
12(6): e0179514, 2017.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28640891
8.
Targeting mutant RAS in patient-derived colorectal cancer organoids by combinatorial drug screening.
Elife;
52016 11 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27845624