Detalhe da pesquisa
1.
Increased S1P induces S1PR2 internalization to blunt the sensitivity of colorectal cancer to 5-fluorouracil via promoting intracellular uracil generation.
Acta Pharmacol Sin;
42(3): 460-469, 2021 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32647340
2.
S1PR2 inhibitors potently reverse 5-FU resistance by downregulating DPD expression in colorectal cancer.
Pharmacol Res;
155: 104717, 2020 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32088343
3.
Corrigendum to "S1PR2 inhibitors potently reverse 5-FU resistance by downregulating DPD expression in colorectal cancer" [Pharmacol Res. 155 (2020) 104717].
Pharmacol Res;
159: 104834, 2020 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32473828
4.
Optimization of permethyl ningalin B analogs as P-glycoprotein inhibitors.
Bioorg Med Chem;
23(17): 5566-73, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26233798
5.
Modification of marine natural product ningalin B and SAR study lead to potent P-glycoprotein inhibitors.
Mar Drugs;
12(10): 5209-21, 2014 Oct 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25329704
6.
Synthesis and evaluation of stereoisomers of methylated catechin and epigallocatechin derivatives on modulating P-glycoprotein-mediated multidrug resistance in cancers.
Eur J Med Chem;
226: 113795, 2021 Dec 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34597896
7.
Novel α-Lipoic Acid/3-n-Butylphthalide Conjugate Enhances Protective Effects against Oxidative Stress and 6-OHDA Induced Neuronal Damage.
ACS Chem Neurosci;
11(11): 1634-1642, 2020 06 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32374999
8.
SphK2 confers 5-fluorouracil resistance to colorectal cancer via upregulating H3K56ac-mediated DPD expression.
Oncogene;
39(29): 5214-5227, 2020 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32546724
9.
Prodrugs of fluoro-substituted benzoates of EGC as tumor cellular proteasome inhibitors and apoptosis inducers.
Int J Mol Sci;
9(6): 951-961, 2008 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19325839
10.
Structural modification of oridonin via DAST induced rearrangement.
RSC Adv;
8(52): 29548-29554, 2018 Aug 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35547324
11.
Extending the structure-activity relationship study of marine natural ningalin B analogues as P-glycoprotein inhibitors.
Eur J Med Chem;
125: 795-806, 2017 Jan 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27750197
12.
Methylation of green tea polyphenols affects their binding to and inhibitory poses of the proteasome beta5 subunit.
Int J Mol Med;
18(4): 625-32, 2006 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16964415
13.
Evaluation of proteasome-inhibitory and apoptosis-inducing potencies of novel (-)-EGCG analogs and their prodrugs.
Int J Mol Med;
15(4): 735-42, 2005 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15754040
14.
Potent and Nontoxic Chemosensitizer of P-Glycoprotein-Mediated Multidrug Resistance in Cancer: Synthesis and Evaluation of Methylated Epigallocatechin, Gallocatechin, and Dihydromyricetin Derivatives.
J Med Chem;
58(11): 4529-49, 2015 Jun 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25985195
15.
Green tea and tea polyphenols in cancer prevention.
Front Biosci;
9: 2618-31, 2004 Sep 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15358585
16.
[Three dimensional quantitative structure-activity relationship of a series of benzocylohepatpyridine farnesyltransferase inhibitors].
Yao Xue Xue Bao;
37(4): 257-62, 2002 Apr.
Artigo
em Zh
| MEDLINE
| ID: mdl-12579819
17.
7-imidazolylalkanamido-1-carboxylalkylbenzo-diazepine, a novel series of farnesyltransferase inhibitors.
Yao Xue Xue Bao;
37(7): 516-21, 2002 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12914320
18.
Sensitizing human multiple myeloma cells to the proteasome inhibitor bortezomib by novel curcumin analogs.
Int J Mol Med;
29(1): 102-6, 2012 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22012631
19.
[An experimental study of the cervical lymphatic imaging in interstitial magnetic resonance lymphography of tongue using Dextran-DTPA-Gd].
Shanghai Kou Qiang Yi Xue;
21(3): 283-6, 2012 Jun.
Artigo
em Zh
| MEDLINE
| ID: mdl-22885488
20.
Synthesis of methylated quercetin derivatives and their reversal activities on P-gp- and BCRP-mediated multidrug resistance tumour cells.
Eur J Med Chem;
54: 413-22, 2012 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22743241