Detalhe da pesquisa
1.
Multi-Target Effect of Aloeresin-A against Bacterial and Host Inflammatory Targets Benefits Contact Lens-Related Keratitis: A Multi-Omics and Quantum Chemical Investigation.
Molecules;
28(19)2023 Oct 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37836798
2.
A rohitukine derivative IIIM-290 induces p53 dependent mitochondrial apoptosis in acute lymphoblastic leukemia cells.
Mol Carcinog;
60(10): 671-683, 2021 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34324743
3.
Safranal inhibits NLRP3 inflammasome activation by preventing ASC oligomerization.
Toxicol Appl Pharmacol;
423: 115582, 2021 07 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34019860
4.
Artemisia amygdalina Upregulates Nrf2 and Protects Neurons Against Oxidative Stress in Alzheimer Disease.
Cell Mol Neurobiol;
39(3): 387-399, 2019 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30725250
5.
Soluble Aß1-42 suppresses TNF-α and activates NLRP3 inflammasome in THP-1 macrophages.
Cytokine;
111: 84-87, 2018 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30125779
6.
The amino analogue of ß-boswellic acid efficiently attenuates the release of pro-inflammatory mediators than its parent compound through the suppression of NF-κB/IκBα signalling axis.
Cytokine;
107: 93-104, 2018 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29229421
7.
Meridianin derivatives as potent Dyrk1A inhibitors and neuroprotective agents.
Bioorg Med Chem Lett;
25(15): 2948-52, 2015 Aug 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26048785
8.
Discovery of 4-acetyl-3-(4-fluorophenyl)-1-(p-tolyl)-5-methylpyrrole as a dual inhibitor of human P-glycoprotein and Staphylococcus aureus Nor A efflux pump.
Org Biomol Chem;
13(19): 5424-31, 2015 May 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25865846
9.
Synthesis and P-glycoprotein induction activity of colupulone analogs.
Org Biomol Chem;
13(19): 5488-96, 2015 May 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25875530
10.
3-(Benzo[d][1,3]dioxol-5-ylamino)-N-(4-fluorophenyl)thiophene-2-carboxamide overcomes cancer chemoresistance via inhibition of angiogenesis and P-glycoprotein efflux pump activity.
Org Biomol Chem;
13(14): 4296-309, 2015 Apr 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25758415
11.
Synthesis, and the antioxidant, neuroprotective and P-glycoprotein induction activity of 4-arylquinoline-2-carboxylates.
Org Biomol Chem;
12(32): 6267-77, 2014 Aug 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25007760
12.
Cancer metastasis: Molecular mechanisms and clinical perspectives.
Pharmacol Ther;
250: 108522, 2023 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37661054
13.
Pharmacoscreening, molecular dynamics, and quantum mechanics of inermin from Panax ginseng: a crucial molecule inhibiting exosomal protein target associated with coronary artery disease progression.
PeerJ;
11: e16481, 2023.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38077444
14.
Activation of lysosomal mediated cell death in the course of autophagy by mTORC1 inhibitor.
Sci Rep;
12(1): 5052, 2022 03 23.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35322026
15.
Loss-of-function mutation in VCP mimics the characteristic pathology as in FTLD-TARDBP.
Autophagy;
17(12): 4502-4503, 2021 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34632910
16.
IIIM-941, a Stilbene Derivative Inhibits NLRP3 Inflammasome Activation by Inducing Autophagy.
Front Pharmacol;
12: 695712, 2021.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34248643
17.
Crocetin promotes clearance of amyloid-ß by inducing autophagy via the STK11/LKB1-mediated AMPK pathway.
Autophagy;
17(11): 3813-3832, 2021 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33404280
18.
Neuronal VCP loss of function recapitulates FTLD-TDP pathology.
Cell Rep;
36(3): 109399, 2021 07 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34289347
19.
Naringenin Upregulates AMPK-Mediated Autophagy to Rescue Neuronal Cells From ß-Amyloid (1-42) Evoked Neurotoxicity.
Mol Neurobiol;
57(8): 3589-3602, 2020 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32542594
20.
Murrayanine Attenuates Lipopolysaccharide-induced Inflammation and Protects Mice from Sepsis-associated Organ Failure.
Basic Clin Pharmacol Toxicol;
124(4): 351-359, 2019 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29719125