Detalhe da pesquisa
1.
Targeted single-cell RNA sequencing of transcription factors enhances the identification of cell types and trajectories.
Genome Res;
31(6): 1069-1081, 2021 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34011578
2.
Single-Cell Transcriptomics Reveals Conserved Regulatory Networks in Human and Mouse Interneuron Development.
Int J Mol Sci;
24(9)2023 May 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37175835
3.
Cellular α-synuclein pathology is associated with bioenergetic dysfunction in Parkinson's iPSC-derived dopamine neurons.
Hum Mol Genet;
28(12): 2001-2013, 2019 06 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30753527
4.
Human-Specific Transcriptome of Ventral and Dorsal Midbrain Dopamine Neurons.
Ann Neurol;
87(6): 853-868, 2020 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32167609
5.
The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function.
Mol Psychiatry;
25(11): 3091-3099, 2020 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31168069
6.
Correction: The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function.
Mol Psychiatry;
25(11): 3107, 2020 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31363164
7.
Dystonia genes functionally converge in specific neurons and share neurobiology with psychiatric disorders.
Brain;
143(9): 2771-2787, 2020 09 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32889528
8.
Epistasis in Neuropsychiatric Disorders.
Trends Genet;
33(4): 256-265, 2017 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28268034
9.
The Parkinson's Disease Genome-Wide Association Study Locus Browser.
Mov Disord;
35(11): 2056-2067, 2020 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32864809
10.
CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice.
Brain;
142(10): 3243-3264, 2019 10 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31504240
11.
RNA sequencing reveals MMP2 and TGFB1 downregulation in LRRK2 G2019S Parkinson's iPSC-derived astrocytes.
Neurobiol Dis;
129: 56-66, 2019 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31085228
12.
Transcriptomic profiling of purified patient-derived dopamine neurons identifies convergent perturbations and therapeutics for Parkinson's disease.
Hum Mol Genet;
26(3): 552-566, 2017 02 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28096185
13.
Systematic Phenomics Analysis Deconvolutes Genes Mutated in Intellectual Disability into Biologically Coherent Modules.
Am J Hum Genet;
98(1): 149-64, 2016 Jan 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26748517
14.
The clustering of functionally related genes contributes to CNV-mediated disease.
Genome Res;
25(6): 802-13, 2015 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25887030
15.
Extensive microRNA-mediated crosstalk between lncRNAs and mRNAs in mouse embryonic stem cells.
Genome Res;
25(5): 655-66, 2015 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25792609
16.
Diverse type 2 diabetes genetic risk factors functionally converge in a phenotype-focused gene network.
PLoS Comput Biol;
13(10): e1005816, 2017 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29059180
17.
Synergistic interactions between Drosophila orthologues of genes spanned by de novo human CNVs support multiple-hit models of autism.
PLoS Genet;
11(3): e1004998, 2015 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25816101
18.
Gene networks underlying convergent and pleiotropic phenotypes in a large and systematically-phenotyped cohort with heterogeneous developmental disorders.
PLoS Genet;
11(3): e1005012, 2015 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25781962
19.
Multiplex High-Throughput Targeted Proteomic Assay To Identify Induced Pluripotent Stem Cells.
Anal Chem;
89(4): 2440-2448, 2017 02 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28192931
20.
Haploinsufficiency predictions without study bias.
Nucleic Acids Res;
43(15): e101, 2015 Sep 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26001969