Detalhe da pesquisa
1.
Activated microglia drive demyelination via CSF1R signaling.
Glia;
69(6): 1583-1604, 2021 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33620118
2.
RAF inhibitors that evade paradoxical MAPK pathway activation.
Nature;
526(7574): 583-6, 2015 Oct 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26466569
3.
Sex- and region-biased depletion of microglia/macrophages attenuates CLN1 disease in mice.
J Neuroinflammation;
17(1): 323, 2020 Oct 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33115477
4.
Mitigation of helium irradiation-induced brain injury by microglia depletion.
J Neuroinflammation;
17(1): 159, 2020 May 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32429943
5.
Macrophage Depletion Ameliorates Peripheral Neuropathy in Aging Mice.
J Neurosci;
38(19): 4610-4620, 2018 05 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29712789
6.
Targeting microglia attenuates neuroinflammation-related neural damage in mice carrying human PLP1 mutations.
Glia;
67(2): 277-290, 2019 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30565754
7.
A limited capacity for microglial repopulation in the adult brain.
Glia;
66(11): 2385-2396, 2018 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30370589
8.
Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor.
N Engl J Med;
373(5): 428-37, 2015 Jul 30.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26222558
9.
Microglia control the spread of neurotropic virus infection via P2Y12 signalling and recruit monocytes through P2Y12-independent mechanisms.
Acta Neuropathol;
136(3): 461-482, 2018 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30027450
10.
Microglial repopulation resolves inflammation and promotes brain recovery after injury.
Glia;
65(6): 931-944, 2017 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28251674
11.
Eliminating microglia in Alzheimer's mice prevents neuronal loss without modulating amyloid-ß pathology.
Brain;
139(Pt 4): 1265-81, 2016 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26921617
12.
Elimination of Microglia Improves Functional Outcomes Following Extensive Neuronal Loss in the Hippocampus.
J Neurosci;
35(27): 9977-89, 2015 Jul 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26156998
13.
Colony-stimulating factor 1 receptor blockade prevents fractionated whole-brain irradiation-induced memory deficits.
J Neuroinflammation;
13(1): 215, 2016 08 30.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27576527
14.
Dynamic microglial modulation of spatial learning and social behavior.
Brain Behav Immun;
55: 6-16, 2016 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26348580
15.
Targeting the colony stimulating factor 1 receptor alleviates two forms of Charcot-Marie-Tooth disease in mice.
Brain;
138(Pt 11): 3193-205, 2015 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26297559
16.
Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma.
Nature;
467(7315): 596-9, 2010 Sep 30.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20823850
17.
Design and pharmacology of a highly specific dual FMS and KIT kinase inhibitor.
Proc Natl Acad Sci U S A;
110(14): 5689-94, 2013 Apr 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23493555
18.
Colony-stimulating factor 1 receptor inhibition prevents microglial plaque association and improves cognition in 3xTg-AD mice.
J Neuroinflammation;
12: 139, 2015 Aug 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26232154
19.
Inhibition of colony stimulating factor-1 receptor improves antitumor efficacy of BRAF inhibition.
BMC Cancer;
15: 356, 2015 May 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25939769
20.
Neurofibroma-associated macrophages play roles in tumor growth and response to pharmacological inhibition.
Acta Neuropathol;
125(1): 159-68, 2013 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23099891