Detalhe da pesquisa
1.
Single-Cell Analysis of Crohn's Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy.
Cell;
178(6): 1493-1508.e20, 2019 09 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31474370
2.
Long-Term Culture Captures Injury-Repair Cycles of Colonic Stem Cells.
Cell;
179(5): 1144-1159.e15, 2019 11 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31708126
3.
TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7-9.
Nature;
581(7808): 316-322, 2020 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32433612
4.
Reverse translation approach generates a signature of penetrating fibrosis in Crohn's disease that is associated with anti-TNF response.
Gut;
71(7): 1289-1301, 2022 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34261752
5.
Single Cell Explorer, collaboration-driven tools to leverage large-scale single cell RNA-seq data.
BMC Genomics;
20(1): 676, 2019 Aug 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31455220
6.
Label-free detection of prostaglandin transporter (SLCO2A1) function and inhibition: insights by wound healing and TRACT assays.
Front Pharmacol;
15: 1372109, 2024.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38783936
7.
Potency switch between CHK1 and MK2: discovery of imidazo[1,2-a]pyrazine- and imidazo[1,2-c]pyrimidine-based kinase inhibitors.
Bioorg Med Chem Lett;
23(10): 2863-7, 2013 May 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23587425
8.
Conformation constraint of anilides enabling the discovery of tricyclic lactams as potent MK2 non-ATP competitive inhibitors.
Bioorg Med Chem Lett;
23(11): 3262-6, 2013 Jun 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23602398
9.
STAT6 phosphorylation inhibitors block eotaxin-3 secretion in bronchial epithelial cells.
Bioorg Med Chem;
20(2): 750-8, 2012 Jan 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22217933
10.
Affinity selection-mass spectrometry screening techniques for small molecule drug discovery.
Curr Opin Chem Biol;
11(5): 518-26, 2007 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17931956
11.
Affinity selection-mass spectrometry and its emerging application to the high throughput screening of G protein-coupled receptors.
Comb Chem High Throughput Screen;
11(6): 427-38, 2008 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18673271
12.
The T-cell receptor beta variable gene promoter is required for efficient V beta rearrangement but not allelic exclusion.
Mol Cell Biol;
24(16): 7015-23, 2004 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15282302
13.
Discovery and characterization of orthosteric and allosteric muscarinic M2 acetylcholine receptor ligands by affinity selection-mass spectrometry.
J Biomol Screen;
11(2): 194-207, 2006 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16490772
14.
The RESOLUTE consortium: unlocking SLC transporters for drug discovery.
Nat Rev Drug Discov;
19(7): 429-430, 2020 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32265506
15.
Erythrocyte-rosetting properties of feline blood lymphocytes and their relationship to monoclonal antibodies to T lymphocytes.
Exp Biol Med (Maywood);
227(9): 771-8, 2002 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12324656
16.
Application of affinity selection-mass spectrometry assays to purification and affinity-based screening of the chemokine receptor CXCR4.
Comb Chem High Throughput Screen;
15(6): 473-85, 2012 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22651846
17.
Discovery and Hit-to-Lead Optimization of Non-ATP Competitive MK2 (MAPKAPK2) Inhibitors.
ACS Med Chem Lett;
2(8): 632-7, 2011 Aug 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24900358
18.
Expression of Gal4-VP16 and Gal4-DNA binding domain under the control of the T lymphocyte-specific lck proximal promoter in transgenic mice.
BMB Rep;
41(8): 575-80, 2008 Aug 31.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18755072
19.
The T cell receptor beta enhancer promotes access and pairing of Dbeta and Jbeta gene segments during V(D)J recombination.
Proc Natl Acad Sci U S A;
100(23): 13465-70, 2003 Nov 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-14593206
20.
Small interfering RNA-mediated gene silencing in T lymphocytes.
J Immunol;
169(10): 5754-60, 2002 Nov 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12421955