Detalhe da pesquisa
1.
Cell type-specific modulation of healthspan by Forkhead family transcription factors in the nervous system.
Proc Natl Acad Sci U S A;
118(8)2021 02 23.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33593901
2.
Fine-tuning autophagy maximises lifespan and is associated with changes in mitochondrial gene expression in Drosophila.
PLoS Genet;
16(11): e1009083, 2020 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33253201
3.
PICALM rescues glutamatergic neurotransmission, behavioural function and survival in a Drosophila model of Aß42 toxicity.
Hum Mol Genet;
29(14): 2420-2434, 2020 08 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32592479
4.
Independent glial subtypes delay development and extend healthy lifespan upon reduced insulin-PI3K signalling.
BMC Biol;
18(1): 124, 2020 09 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32928209
5.
Deficiency in Neuronal TGF-ß Signaling Leads to Nigrostriatal Degeneration and Activation of TGF-ß Signaling Protects against MPTP Neurotoxicity in Mice.
J Neurosci;
37(17): 4584-4592, 2017 04 26.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28363982
6.
A Drosophila Model of Neuronopathic Gaucher Disease Demonstrates Lysosomal-Autophagic Defects and Altered mTOR Signalling and Is Functionally Rescued by Rapamycin.
J Neurosci;
36(46): 11654-11670, 2016 11 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27852774
7.
Cyclooxygenase inhibition targets neurons to prevent early behavioural decline in Alzheimer's disease model mice.
Brain;
139(Pt 7): 2063-81, 2016 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27190010
8.
Suppression of Alzheimer-associated inflammation by microglial prostaglandin-E2 EP4 receptor signaling.
J Neurosci;
34(17): 5882-94, 2014 Apr 23.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24760848
9.
Suppression of inflammation with conditional deletion of the prostaglandin E2 EP2 receptor in macrophages and brain microglia.
J Neurosci;
33(40): 16016-32, 2013 Oct 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24089506
10.
Inflammatory prostaglandin E2 signaling in a mouse model of Alzheimer disease.
Ann Neurol;
72(5): 788-98, 2012 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22915243
11.
Plum modulates Myoglianin and regulates synaptic function in D. melanogaster.
Open Biol;
13(9): 230171, 2023 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37699519
12.
Protein retention in the endoplasmic reticulum rescues Aß toxicity in Drosophila.
Neurobiol Aging;
132: 154-174, 2023 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37837732
13.
The prostaglandin E2 E-prostanoid 4 receptor exerts anti-inflammatory effects in brain innate immunity.
J Immunol;
184(12): 7207-18, 2010 Jun 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20483760
14.
Mitochondria Dysfunction in Frontotemporal Dementia/Amyotrophic Lateral Sclerosis: Lessons From Drosophila Models.
Front Neurosci;
15: 786076, 2021.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34899176
15.
Shifting equilibriums in Alzheimer's disease: the complex roles of microglia in neuroinflammation, neuronal survival and neurogenesis.
Neural Regen Res;
15(7): 1208-1219, 2020 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31960800
16.
The neuronal receptor tyrosine kinase Alk is a target for longevity.
Aging Cell;
19(5): e13137, 2020 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32291952
17.
Parkinson's Disease: Mitochondria Parked at the ER Hit the Snooze Button.
Neuron;
98(6): 1059-1061, 2018 06 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29953866
18.
Insertional inactivation of the L13a ribosomal protein gene of Drosophila melanogaster identifies a new Minute locus.
Gene;
368: 46-52, 2006 Mar 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16326033
19.
Untangling the Web: Toxic and Protective Effects of Neuroinflammation and PGE2 Signaling in Alzheimer's Disease.
ACS Chem Neurosci;
7(4): 454-63, 2016 Apr 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26979823
20.
Inflammatory Cyclooxygenase Activity and PGE2 Signaling in Models of Alzheimer's Disease.
Curr Immunol Rev;
11(2): 125-131, 2015 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28413375