Detalhe da pesquisa
1.
Reforms of regulatory pathways for approval of new antineoplastic drugs in Japan from 2004 to 2019 and accompanying changes in pivotal clinical trial designs.
Invest New Drugs;
40(1): 142-150, 2022 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34417913
2.
Lamellarin 14, a derivative of marine alkaloids, inhibits the T790M/C797S mutant epidermal growth factor receptor.
Cancer Sci;
112(5): 1963-1974, 2021 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33544933
3.
Discovery of Inhibitors of Membrane Traffic from a Panel of Clinically Effective Anticancer Drugs.
Biol Pharm Bull;
42(5): 814-818, 2019 May 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30787205
4.
Family-wide Analysis of the Inhibition of Arf Guanine Nucleotide Exchange Factors with Small Molecules: Evidence of Unique Inhibitory Profiles.
Biochemistry;
56(38): 5125-5133, 2017 09 26.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28858527
5.
M-COPA, a novel Golgi system disruptor, suppresses apoptosis induced by Shiga toxin.
Genes Cells;
21(8): 901-6, 2016 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27302278
6.
Abdominal Infection Suppresses the Number and Activity of Intrahepatic Natural Killer Cells and Promotes Tumor Growth in a Murine Liver Metastasis Model.
Ann Surg Oncol;
23 Suppl 2: S257-65, 2016 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25752891
7.
Basal expression of insulin-like growth factor 1 receptor determines intrinsic resistance of cancer cells to a phosphatidylinositol 3-kinase inhibitor ZSTK474.
Cancer Sci;
106(2): 171-8, 2015 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25483727
8.
Comprehensive transcriptomic analysis of molecularly targeted drugs in cancer for target pathway evaluation.
Cancer Sci;
106(7): 909-20, 2015 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25911996
9.
Identification of a molecular target of kurahyne, an apoptosis-inducing lipopeptide from marine cyanobacterial assemblages.
Bioorg Med Chem Lett;
25(22): 5295-8, 2015 Nov 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26428873
10.
Synthesis of dansyl-labeled probe of thiophene analogue of annonaceous acetogenins for visualization of cell distribution and growth inhibitory activity toward human cancer cell lines.
Bioorg Med Chem;
23(6): 1276-83, 2015 Mar 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25684427
11.
Ridaifen G, tamoxifen analog, is a potent anticancer drug working through a combinatorial association with multiple cellular factors.
Bioorg Med Chem;
23(18): 6118-24, 2015 Sep 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26314924
12.
Extensive analysis of signaling pathway molecules in breast cancer: association with clinicopathological characteristics.
Int J Clin Oncol;
20(3): 490-8, 2015 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25312293
13.
Antitumor effects of tyropeptin-boronic acid derivatives: New proteasome inhibitors.
Cancer Sci;
105(12): 1609-15, 2014 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25251038
14.
In vitro multifaceted activities of a specific group of novel phosphatidylinositol 3-kinase inhibitors on hotspot mutant PIK3CA.
Invest New Drugs;
32(6): 1134-43, 2014 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25152245
15.
In vitro antitumor activity of stellettin B, a triterpene from marine sponge Jaspis stellifera, on human glioblastoma cancer SF295 cells.
Mar Drugs;
12(7): 4200-13, 2014 Jul 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25028795
16.
Identification of transporters associated with Etoposide sensitivity of stomach cancer cell lines and methotrexate sensitivity of breast cancer cell lines by quantitative targeted absolute proteomics.
Mol Pharmacol;
83(2): 490-500, 2013 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23197647
17.
AMF-26, a novel inhibitor of the Golgi system, targeting ADP-ribosylation factor 1 (Arf1) with potential for cancer therapy.
J Biol Chem;
287(6): 3885-97, 2012 Feb 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22158626
18.
Development of a gene expression database and related analysis programs for evaluation of anticancer compounds.
Cancer Sci;
104(3): 360-8, 2013 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23176546
19.
Novel tamoxifen derivative Ridaifen-B induces Bcl-2 independent autophagy without estrogen receptor involvement.
Biochem Biophys Res Commun;
435(4): 657-63, 2013 Jun 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23688426
20.
Search for novel anti-tumor agents from ridaifens using JFCR39, a panel of human cancer cell lines.
Biol Pharm Bull;
36(6): 1008-16, 2013.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23575219