Detalhe da pesquisa
1.
Engineering Pancreatic Islets to Transiently Codisplay on Their Surface Thrombomodulin and CD47 Immunomodulatory Proteins as a Means of Mitigating Instant Blood-Mediated Inflammatory Reaction following Intraportal Transplantation.
J Immunol;
212(12): 1971-1980, 2024 Jun 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38709159
2.
Engineering pancreatic islets with a novel form of thrombomodulin protein to overcome early graft loss triggered by instant blood-mediated inflammatory reaction.
Am J Transplant;
23(5): 619-628, 2023 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36863480
3.
Delayed graft rejection in autoimmune islet transplantation via biomaterial immunotherapy.
Am J Transplant;
23(11): 1709-1722, 2023 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37543091
4.
A novel agonist of 4-1BB costimulatory receptor shows therapeutic efficacy against a tobacco carcinogen-induced lung cancer.
Cancer Immunol Immunother;
72(11): 3567-3579, 2023 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37605009
5.
Localized Immunomodulation with PD-L1 Results in Sustained Survival and Function of Allogeneic Islets without Chronic Immunosuppression.
J Immunol;
204(10): 2840-2851, 2020 05 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32253240
6.
Immune checkpoint CD47 molecule engineered islets mitigate instant blood-mediated inflammatory reaction and show improved engraftment following intraportal transplantation.
Am J Transplant;
20(10): 2703-2714, 2020 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32342638
7.
Pancreatic islets engineered with a FasL protein induce systemic tolerance at the induction phase that evolves into long-term graft-localized immune privilege.
Am J Transplant;
20(5): 1285-1295, 2020 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31850658
8.
Local immunomodulation Fas ligand-engineered biomaterials achieves allogeneic islet graft acceptance.
Nat Mater;
17(8): 732-739, 2018 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29867165
9.
Novel technologies to engineer graft for tolerance induction.
Curr Opin Organ Transplant;
21(1): 74-80, 2016 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26626421
10.
Facilitating cells in tolerance induction for kidney transplantation.
Curr Opin Organ Transplant;
20(1): 57-63, 2015 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25522139
11.
Killer Treg cells ameliorate inflammatory insulitis in non-obese diabetic mice through local and systemic immunomodulation.
Int Immunol;
25(8): 485-94, 2013 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23657001
12.
Protocol for transplanting pancreatic islets into the parametrial fat pad of female mice.
STAR Protoc;
5(1): 102816, 2024 Mar 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38180833
13.
Bending the Rules: Amplifying PD-L1 Immunoregulatory Function Through Flexible Polyethylene Glycol Synthetic Linkers.
Tissue Eng Part A;
30(7-8): 299-313, 2024 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38318841
14.
Oncolytic Adenovirus Armed with a Novel Agonist of the CD137 Immune Checkpoint Stimulator Suppresses Tumor Growth.
Vaccines (Basel);
12(3)2024 Mar 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38543974
15.
Pancreatic islets engineered with SA-FasL protein establish robust localized tolerance by inducing regulatory T cells in mice.
J Immunol;
187(11): 5901-9, 2011 Dec 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22068235
16.
Engineering donor lymphocytes with Fas ligand protein effectively prevents acute graft-versus-host disease.
Blood Adv;
7(10): 2181-2195, 2023 05 23.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36780582
17.
Bioengineered omental transplant site promotes pancreatic islet allografts survival in non-human primates.
Cell Rep Med;
4(3): 100959, 2023 03 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36863336
18.
A modified surgical procedure using minimally invasive ileocolic vein perfusion in a mouse intrahepatic islet transplant model.
STAR Protoc;
3(2): 101416, 2022 06 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35620067
19.
Fas Ligand-Modified Scaffolds Protect Stem Cell Derived ß-Cells by Modulating Immune Cell Numbers and Polarization.
ACS Appl Mater Interfaces;
2022 Dec 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36533683
20.
A hydrogel platform for co-delivery of immunomodulatory proteins for pancreatic islet allografts.
J Biomed Mater Res A;
110(11): 1728-1737, 2022 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35841329