Detalhe da pesquisa
1.
TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS.
Cell;
183(3): 636-649.e18, 2020 10 29.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33031745
2.
Caspase-8-driven apoptotic and pyroptotic crosstalk causes cell death and IL-1ß release in X-linked inhibitor of apoptosis (XIAP) deficiency.
EMBO J;
42(5): e110468, 2023 03 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36647737
3.
NLRP1 variant M1184V decreases inflammasome activation in the context of DPP9 inhibition and asthma severity.
J Allergy Clin Immunol;
147(6): 2134-2145.e20, 2021 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33378691
4.
Rab6b localizes to the Golgi complex in murine macrophages and promotes tumor necrosis factor release in response to mycobacterial infection.
Immunol Cell Biol;
99(10): 1067-1076, 2021 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34555867
5.
Human DPP9 represses NLRP1 inflammasome and protects against autoinflammatory diseases via both peptidase activity and FIIND domain binding.
J Biol Chem;
293(49): 18864-18878, 2018 12 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30291141
6.
RP105 Engages Phosphatidylinositol 3-Kinase p110δ To Facilitate the Trafficking and Secretion of Cytokines in Macrophages during Mycobacterial Infection.
J Immunol;
195(8): 3890-900, 2015 Oct 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26371254
7.
Recombinant Wnt3a and Wnt5a elicit macrophage cytokine production and tolerization to microbial stimulation via Toll-like receptor 4.
Eur J Immunol;
44(5): 1480-90, 2014 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24643512
8.
Stray self-nucleic acids: the emerging drivers of neurodegeneration.
Trends Cell Biol;
33(6): 451-454, 2023 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36907819
9.
Organellar homeostasis and innate immune sensing.
Nat Rev Immunol;
22(9): 535-549, 2022 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35197578
10.
Deficiency in coatomer complex I causes aberrant activation of STING signalling.
Nat Commun;
13(1): 2321, 2022 04 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35484149
11.
DPP9 deficiency: An inflammasomopathy that can be rescued by lowering NLRP1/IL-1 signaling.
Sci Immunol;
7(75): eabi4611, 2022 09 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36112693
12.
Protein kinase R is an innate immune sensor of proteotoxic stress via accumulation of cytoplasmic IL-24.
Sci Immunol;
7(68): eabi6763, 2022 02 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35148201
13.
Whole-genome sequencing reveals that variants in the Interleukin 18 Receptor Accessory Protein 3'UTR protect against ALS.
Nat Neurosci;
25(4): 433-445, 2022 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35361972
14.
Mechanisms of NLRP1-Mediated Autoinflammatory Disease in Humans and Mice.
J Mol Biol;
430(2): 142-152, 2018 01 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28733143
15.
NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease.
Nat Commun;
9(1): 3728, 2018 09 13.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30214011
16.
T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles.
Arthritis Res Ther;
14(3): R118, 2012 May 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22594821