Detalhe da pesquisa
1.
Dissection of a Down syndrome-associated trisomy to separate the gene dosage-dependent and -independent effects of an extra chromosome.
Hum Mol Genet;
32(13): 2205-2218, 2023 06 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37014740
2.
Impact of increased APP gene dose in Down syndrome and the Dp16 mouse model.
Alzheimers Dement;
18(6): 1203-1234, 2022 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34757693
3.
Analysis of motor dysfunction in Down Syndrome reveals motor neuron degeneration.
PLoS Genet;
14(5): e1007383, 2018 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29746474
4.
Corrigendum: Retrotransposition creates sloping shores: a graded influence of hypomethylated CpG islands on flanking CpG sites.
Genome Res;
30(2): 313, 2020 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32079650
5.
Retrotransposition creates sloping shores: a graded influence of hypomethylated CpG islands on flanking CpG sites.
Genome Res;
25(8): 1135-46, 2015 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25995269
6.
Evidence that increased Kcnj6 gene dose is necessary for deficits in behavior and dentate gyrus synaptic plasticity in the Ts65Dn mouse model of Down syndrome.
Neurobiol Dis;
103: 1-10, 2017 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28342823
7.
Genetic dissection of the Down syndrome critical region.
Hum Mol Genet;
24(22): 6540-51, 2015 Nov 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26374847
8.
Human chromosome 21 orthologous region on mouse chromosome 17 is a major determinant of Down syndrome-related developmental cognitive deficits.
Hum Mol Genet;
23(3): 578-89, 2014 Feb 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24041763
9.
Mouse-based genetic modeling and analysis of Down syndrome.
Br Med Bull;
120(1): 111-122, 2016 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27789459
10.
Engineered chromosome-based genetic mapping establishes a 3.7 Mb critical genomic region for Down syndrome-associated heart defects in mice.
Hum Genet;
133(6): 743-53, 2014 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24362460
11.
Altered tongue muscle contractile properties coincide with altered swallow function in the adult Ts65Dn mouse model of down syndrome.
Front Neurol;
15: 1384572, 2024.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38585362
12.
SARS-CoV-2 Infection Causes Heightened Disease Severity and Mortality in a Mouse Model of Down Syndrome.
Biomedicines;
12(3)2024 Feb 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38540156
13.
Lgi1 null mutant mice exhibit myoclonic seizures and CA1 neuronal hyperexcitability.
Hum Mol Genet;
19(9): 1702-11, 2010 May 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20130004
14.
A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions.
Hum Mol Genet;
19(14): 2780-91, 2010 Jul 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20442137
15.
Hearing impairment in murine model of Down syndrome.
Front Genet;
13: 936128, 2022.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35991545
16.
Genetic analysis of Down syndrome-associated heart defects in mice.
Hum Genet;
130(5): 623-32, 2011 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21442329
17.
Mouse models for Down syndrome-associated developmental cognitive disabilities.
Dev Neurosci;
33(5): 404-13, 2011.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21865664
18.
Coat Color-Facilitated Efficient Generation and Analysis of a Mouse Model of Down Syndrome Triplicated for All Human Chromosome 21 Orthologous Regions.
Genes (Basel);
12(8)2021 08 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34440389
19.
Mechanistic Analysis of Age-Related Clinical Manifestations in Down Syndrome.
Front Aging Neurosci;
13: 700280, 2021.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34276349
20.
Homozygous inactivation of the LGI1 gene results in hypomyelination in the peripheral and central nervous systems.
J Neurosci Res;
88(15): 3328-36, 2010 Nov 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20857514