Detalhe da pesquisa
1.
Two-Year observational study of autonomic skin function in patients with Parkinson's disease compared to healthy individuals.
Eur J Neurol;
30(5): 1281-1292, 2023 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36773001
2.
Mutant three-repeat tau expression initiates retinal ganglion cell death through Caspase-2.
Neurobiol Dis;
152: 105277, 2021 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33516874
3.
The subcellular arrangement of alpha-synuclein proteoforms in the Parkinson's disease brain as revealed by multicolor STED microscopy.
Acta Neuropathol;
142(3): 423-448, 2021 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34115198
4.
Systematic Assessment of 10 Biomarker Candidates Focusing on α-Synuclein-Related Disorders.
Mov Disord;
36(12): 2874-2887, 2021 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34363416
5.
Immunohistochemical Detection of Synuclein Pathology in Skin in Idiopathic Rapid Eye Movement Sleep Behavior Disorder and Parkinsonism.
Mov Disord;
36(4): 895-904, 2021 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33232556
6.
First-in-human assessment of PRX002, an anti-α-synuclein monoclonal antibody, in healthy volunteers.
Mov Disord;
32(2): 211-218, 2017 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27886407
7.
Reducing C-terminal-truncated alpha-synuclein by immunotherapy attenuates neurodegeneration and propagation in Parkinson's disease-like models.
J Neurosci;
34(28): 9441-54, 2014 Jul 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25009275
8.
The mechanism of action, pharmacological characteristics, and clinical utility of the amyloid depleter birtamimab for the potential treatment of AL amyloidosis.
Leuk Lymphoma;
: 1-11, 2024 Apr 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38600883
9.
Neutralization of soluble, synaptotoxic amyloid ß species by antibodies is epitope specific.
J Neurosci;
32(8): 2696-702, 2012 Feb 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22357853
10.
Vascular alterations in PDAPP mice after anti-Aß immunotherapy: Implications for amyloid-related imaging abnormalities.
Alzheimers Dement;
9(5 Suppl): S105-15, 2013 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23583235
11.
Reliability and validity of the Roche PD Mobile Application for remote monitoring of early Parkinson's disease.
Sci Rep;
12(1): 12081, 2022 07 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35840753
12.
Takusan: a large gene family that regulates synaptic activity.
Neuron;
55(1): 69-85, 2007 Jul 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17610818
13.
Hypoxia enhances S-nitrosylation-mediated NMDA receptor inhibition via a thiol oxygen sensor motif.
Neuron;
53(1): 53-64, 2007 Jan 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17196530
14.
A Phase II Study to Evaluate the Safety and Efficacy of Prasinezumab in Early Parkinson's Disease (PASADENA): Rationale, Design, and Baseline Data.
Front Neurol;
12: 705407, 2021.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34659081
15.
C-terminal calcium binding of α-synuclein modulates synaptic vesicle interaction.
Nat Commun;
9(1): 712, 2018 02 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29459792
16.
Safety and Tolerability of Multiple Ascending Doses of PRX002/RG7935, an Anti-α-Synuclein Monoclonal Antibody, in Patients With Parkinson Disease: A Randomized Clinical Trial.
JAMA Neurol;
75(10): 1206-1214, 2018 10 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29913017
17.
Anti-α-synuclein immunotherapy reduces α-synuclein propagation in the axon and degeneration in a combined viral vector and transgenic model of synucleinopathy.
Acta Neuropathol Commun;
5(1): 7, 2017 01 13.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28086964
18.
The Search for a Peripheral Biopsy Indicator of α-Synuclein Pathology for Parkinson Disease.
J Neuropathol Exp Neurol;
76(1): 2-15, 2017 01 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28069931
19.
Cutaneous Autonomic Pilomotor Testing to Unveil the Role of Neuropathy Progression in Early Parkinson's Disease (CAPTURE PD): Protocol for a Multicenter Study.
Front Neurol;
8: 212, 2017.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28603514
20.
Monitoring Blood-Brain Barrier Integrity Following Amyloid-ß Immunotherapy Using Gadolinium-Enhanced MRI in a PDAPP Mouse Model.
J Alzheimers Dis;
54(2): 723-35, 2016 09 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27567811