Detalhe da pesquisa
1.
Structure-guided design of potent JAK1-selective inhibitors based on 4-amino-7H-pyrrolo[2,3-d]pyrimidine with anti-inflammatory efficacy.
Arch Pharm (Weinheim);
357(4): e2300591, 2024 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38185750
2.
Experiments on the Capillary Force of a Clam-Shell Droplet on Fibers by 3-D Model Reconstruction.
Langmuir;
39(33): 11520-11528, 2023 Aug 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37561397
3.
Doped nanomaterial facilitates 3D printing target plate for rapid detection of alkaloids in laser desorption/ionization mass spectrometry.
Anal Bioanal Chem;
415(27): 6825-6838, 2023 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37848578
4.
Discovery of novel phenyl triazole analogs as TRK/ALK dual inhibitors with prospective antitumor effects.
Bioorg Chem;
136: 106563, 2023 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37121107
5.
Identification of highly potent 2,4-diarylaminopyrimidine analogs of a typical piperidinyl-4-ol moiety as promising antitumor ALK inhibitors.
Arch Pharm (Weinheim);
356(12): e2300416, 2023 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37737557
6.
Facile Transformation from Rofecoxib to a New Near-Infrared Lipid Droplet Fluorescent Probe and Its Investigations on AIE Property, Solvatochromism and Mechanochromism.
Molecules;
28(4)2023 Feb 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36838802
7.
1-(4-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-3-methoxyphenyl)-3-(2-(dimethylamino)ethyl)imidazolidin-2-one (ZX-42) inhibits cell proliferation and induces apoptosis via inhibiting ALK and its downstream pathways in Karpas299 cells.
Toxicol Appl Pharmacol;
450: 116156, 2022 09 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35803438
8.
Fragment-based discovery of novel phenyltriazolyl derivatives as allosteric type-I1/2 ALK inhibitors with promising antitumor effects.
Bioorg Med Chem Lett;
75: 128990, 2022 11 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36113668
9.
Design, synthesis and anti-tumor efficacy of novel phenyl thiazole/triazole derivatives as selective TrkA inhibitors.
Bioorg Med Chem;
72: 116995, 2022 10 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36095945
10.
Novel imidazo[1,2-a]pyridine derivatives as potent ATX allosteric inhibitors: Design, synthesis and promising in vivo anti-fibrotic efficacy in mice lung model.
Bioorg Chem;
120: 105590, 2022 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34998121
11.
Transcriptome sequencing and signal transduction for the enhanced tanshinone production in Salvia miltiorrhiza hairy roots induced by Trichoderma atroviride D16 polysaccharide fraction.
Biosci Biotechnol Biochem;
86(8): 1049-1059, 2022 Jul 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35675224
12.
Anti-fibrosis attributes: UHPLC-MS/MS-based pharmacokinetics profiling of a novel autotaxin inhibitor with excellent in vivo efficacy in rat.
Biomed Chromatogr;
36(4): e5301, 2022 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34928514
13.
Hybrid imidazo[1,2-a]pyridine analogs as potent ATX inhibitors with concrete in vivo antifibrosis effect.
Arch Pharm (Weinheim);
355(10): e2200171, 2022 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35661405
14.
[Modified Shenqi Dihuang Decoction acts on hormone-sensitive prostate cancer by inhibiting glycolysis through the PI3K/Akt /mTOR signaling pathway].
Zhonghua Nan Ke Xue;
28(1): 48-55, 2022 Jan.
Artigo
em Zh
| MEDLINE
| ID: mdl-37459078
15.
An update on allosteric modulators as a promising strategy targeting histone methyltransferase.
Pharmacol Res;
172: 105865, 2021 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34474102
16.
Rapid nanowelding of silver nanowires by focused-light-scanning for high-performance flexible transparent electrodes.
Nanotechnology;
32(50)2021 Oct 13.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34571500
17.
Discovery and antitumor activity of Benzo[d]imidazol-containing 2,4-diarylaminopyrimidine analogues as ALK inhibitors with mutation-combating effects.
Bioorg Med Chem;
37: 116108, 2021 05 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33756437
18.
Harmine-inspired design and synthesis of benzo[d]imidazo[2,1-b]thiazole derivatives bearing 1,3,4-oxadiazole moiety as potential tumor suppressors.
Bioorg Med Chem;
46: 116367, 2021 09 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34425477
19.
Discovery of novel 2-phenylamino-4-prolylpyrimidine derivatives as TRK/ALK dual inhibitors with promising antitumor effects.
Bioorg Med Chem;
47: 116396, 2021 10 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34534734
20.
Design, synthesis and anti-fibrosis evaluation of imidazo[1,2-a]pyridine derivatives as potent ATX inhibitors.
Bioorg Med Chem;
46: 116362, 2021 09 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34428714