RESUMO
The present study aims to examine the impact of response readiness on visuomotor processes triggered by subliminal stimuli using a mixed paradigm involving the masked prime paradigm and a foreperiod paradigm. Experiment 1 ensured that response readiness was successfully manipulated in the mixed paradigm. Importantly, Experiment 2 found that the negative compatibility effect (NCE; a behavioral indicator of subliminal visuomotor processes) disappeared and that response time lost its power to modulate the compatibility effect (CE) with reduced response readiness (due to temporal uncertainty). These results of CEs both independent of response latency and across different levels of response latency indicate that response readiness is a prerequisite for obtaining the NCE. The findings suggest that automatic processing of subliminal stimuli is susceptible to top-down control for reducing the interference of irrelevant information, which ensures a high degree of adaptability and flexibility of our cognitive system in interactions with the changing environment.
Assuntos
Atividade Motora/fisiologia , Mascaramento Perceptivo/fisiologia , Desempenho Psicomotor/fisiologia , Tempo de Reação/fisiologia , Incerteza , Percepção Visual/fisiologia , Adolescente , Adulto , Feminino , Humanos , Masculino , Estimulação Subliminar , Adulto JovemRESUMO
The inherent brittleness and low sustainability of YBa2Cu3O7 -x (YBCO) bulk superconductor seriously impede its wide applications. It is a great challenge to achieve toughening of this material and maintain its invariable superconductivity at the same time. Here, we fabricate bulk YBCO composite superconductor with a density of 2.15 g cm-3, which consists of interlocking dual network construction and shows high toughness and durability. The results show that its unit normalized fracture energy at 77 K reaches 638.6 kN m-2, which is â¼14.8 times that of YBCO bulk prepared by the top-seeded melt textured growth (TSMTG) method. Its critical current shows no degradation during the toughening process. Moreover, after 10 000 cycles, the sample does not fracture with the decay of critical current at 4 K of 14.6% whereas the TSMTG sample fractures only after 25 cycles.
RESUMO
Background: Figure-ground segregation is a necessary process for accurate visual recognition. Previous neurophysiological and human brain imaging studies have suggested that foreground-background segregation relies on both enhanced foreground representation and suppressed background representation. However, in humans, it is not known when and how foreground and background processing play a role in texture segregation. Methods: To answer this question, it is crucial to extract and dissociate the neural signals elicited by the foreground and background of a figure texture with high temporal resolution. Here, we combined an electroencephalogram (EEG) recording and a temporal response function (TRF) approach to specifically track the neural responses to the foreground and background of a figure texture from the overall EEG recordings in the luminance-tracking TRF. A uniform texture was included as a neutral condition. The texture segregation visual evoked potential (tsVEP) was calculated by subtracting the uniform TRF from the foreground and background TRFs, respectively, to index the specific segregation activity. Results: We found that the foreground and background of a figure texture were processed differently during texture segregation. In the posterior region of the brain, we found a negative component for the foreground tsVEP in the early stage of foreground-background segregation, and two negative components for the background tsVEP in the early and late stages. In the anterior region, we found a positive component for the foreground tsVEP in the late stage, and two positive components for the background tsVEP in the early and late stages of texture processing. Discussion: In this study we investigated the temporal profile of foreground and background processing during texture segregation in human participants at a high time resolution. The results demonstrated that the foreground and background jointly contribute to figure-ground segregation in both the early and late phases of texture processing. Our findings provide novel evidence for the neural correlates of foreground-background modulation during figure-ground segregation in humans.
Assuntos
Potenciais Evocados Visuais , Reconhecimento Visual de Modelos , Humanos , Reconhecimento Visual de Modelos/fisiologia , Visão Ocular , Eletroencefalografia/métodos , EncéfaloRESUMO
Dynamically evaluating the outcomes of our actions and thoughts is a fundamental cognitive ability. Given its excellent temporal resolution, the event-related potential (ERP) technology has been used to address this issue. The feedback-related negativity (FRN) component of ERPs has been studied intensively with the averaged linked mastoid reference method (LM). However, it is unknown whether FRN can be induced by an expectancy violation in an antonym relations context and whether LM is the most suitable reference approach. To address these issues, the current research directly compared the ERP components induced by expectancy violations in antonym expectation and gambling tasks with a within-subjects design and investigated the effect of the reference approach on the experimental effects. Specifically, we systematically compared the influence of the LM, reference electrode standardization technique (REST) and average reference (AVE) approaches on the amplitude, scalp distribution and magnitude of ERP effects as a function of expectancy violation type. The expectancy deviation in the antonym expectation task elicited an N400 effect that differed from the FRN effect induced in the gambling task; this difference was confirmed by all the three reference methods. Both the amplitudes of the ERP effects (N400 and FRN) and the magnitude as the expectancy violation increased were greater under the LM approach than those under the REST approach, followed by those under the AVE approach. Based on the statistical results, the electrode sites that showed the N400 and FRN effects critically depended on the reference method, and the results of the REST analysis were consistent with previous ERP studies. Combined with evidence from simulation studies, we suggest that REST is an optional reference method to be used in future ERP data analysis.
RESUMO
A prime-target interference task was used to investigate the effects of cognitive aging on reactive and proactive control after eliminating frequency confounds and feature repetitions from the cognitive control measures. We used distributional analyses to explore the dynamics of the two control functions by distinguishing the strength of incorrect response capture and the efficiency of suppression control. For reactive control, within-trial conflict control and between-trial conflict adaption were analyzed. The statistical analysis showed that there were no reliable between-trial conflict adaption effects for either young or older adults. For within-trial conflict control, the results revealed that older adults showed larger interference effects on mean RT and mean accuracy. Distributional analyses showed that the decline mainly stemmed from inefficient suppression rather than from stronger incorrect responses. For proactive control, older adults showed comparable proactive conflict resolution to young adults on mean RT and mean accuracy. Distributional analyses showed that older adults were as effective as younger adults in adjusting their responses based on congruency proportion information to minimize automatic response capture and actively suppress the direct response activation. The results suggest that older adults were less proficient at suppressing interference after conflict was detected but can anticipate and prevent inference in response to congruency proportion manipulation. These results challenge earlier views that older adults have selective deficits in proactive control but intact reactive control.
RESUMO
OBJECTIVES: Despite extensive childhood immunization, pertussis remains one of the world's leading causes of vaccine-preventable deaths. Incidence of pertussis in adolescents and adults has increased in many countries despite high vaccination coverage. In China, booster vaccinations against diphtheria, tetanus and pertussis are not used in adults, and little is known about pertussis incidence in the age group. The aim of this study was to determine seroprevalence of IgG antibodies to pertussis toxin (PT) and diphtheria among adults in China. METHODS: Blood samples were obtained from 210 healthy adults aged 18-50 years in Weifang city, China during the period of May and June 2010. Serum IgG antibodies against PT (anti-PT IgG) and diphtheria were determined by the commercial ELISA kits, respectively. According to the kit, concentration of anti-PT IgG higher than 30 IU/mL was considered positive. An antibody concentration of ≥ 0.1 IU/mL was defined as evidence of seroprotection against diphtheria. RESULTS: The mean concentration of anti-PT IgG antibodies was 9.95 IU/mL (95% confidence interval (CI) 8.45-11.44). Eleven (5.24%) of the studied subjects were proved to be seropositive to pertussis. Of the 210 subjects, 161 (76.6%) had anti-diphtheria antibody concentration ≥ 0.1 IU/mL and 49 (23.3%) had the antibody concentration between 0.01 and 0.099 IU/mL. CONCLUSIONS: Our study indicated that about 5% of adults aged 18-50 years had positive anti-PT IgG antibodies, suggesting that adult pertussis is not uncommon in China. Although a high proportion of studied subjects had a protective level of immunity against diphtheria, the antibody level decreased with the increasing age of adults. Booster vaccinations against pertussis should be considered in adults in China.