Detalhe da pesquisa
1.
Generation of rationally-designed nerve growth factor (NGF) variants with receptor specificity.
Biochem Biophys Res Commun;
495(1): 700-705, 2018 01 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29108999
2.
Evaluating CHARGE syndrome in congenital hypogonadotropic hypogonadism patients harboring CHD7 variants.
Genet Med;
20(8): 872-881, 2018 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29144511
3.
An improved understanding of TNFL/TNFR interactions using structure-based classifications.
Trends Biochem Sci;
37(9): 353-63, 2012 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22789664
4.
Engineering of weak helper interactions for high-efficiency FRET probes.
Nat Methods;
10(10): 1021-7, 2013 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23995386
5.
Kinetics in signal transduction pathways involving promiscuous oligomerizing receptors can be determined by receptor specificity: apoptosis induction by TRAIL.
Mol Cell Proteomics;
11(3): M111.013730, 2012 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22213832
6.
The design and characterization of receptor-selective APRIL variants.
J Biol Chem;
287(44): 37434-46, 2012 Oct 26.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22961987
7.
A screen for MeCP2-TBL1 interaction inhibitors using a luminescence-based assay.
Sci Rep;
13(1): 3868, 2023 03 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36890145
8.
A novel classification system to predict the pathogenic effects of CHD7 missense variants in CHARGE syndrome.
Hum Mutat;
33(8): 1251-60, 2012 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22539353
9.
Building blocks for protein interaction devices.
Nucleic Acids Res;
38(8): 2645-62, 2010 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20215443
10.
Targeting AML through DR4 with a novel variant of rhTRAIL.
J Cell Mol Med;
15(10): 2216-31, 2011 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21070598
11.
Identification and optimization of molecular glue compounds that inhibit a noncovalent E2 enzyme-ubiquitin complex.
Sci Adv;
7(44): eabi5797, 2021 Oct 29.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34705497
12.
Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality.
J Cell Biol;
219(10)2020 10 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32785687
13.
Imipridone Anticancer Compounds Ectopically Activate the ClpP Protease and Represent a New Scaffold for Antibiotic Development.
Genetics;
214(4): 1103-1120, 2020 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32094149
14.
Enhancement of antitumor properties of rhTRAIL by affinity increase toward its death receptors.
Biochemistry;
48(10): 2180-91, 2009 Mar 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19236007
15.
Loop grafting of Bacillus subtilis lipase A: inversion of enantioselectivity.
Chem Biol;
15(8): 782-9, 2008 Aug 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18721749
16.
A novel genetic selection system for improved enantioselectivity of Bacillus subtilis lipase A.
Chembiochem;
9(7): 1110-5, 2008 May 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18383241
17.
RET-familial medullary thyroid carcinoma mutants Y791F and S891A activate a Src/JAK/STAT3 pathway, independent of glial cell line-derived neurotrophic factor.
Cancer Res;
65(5): 1729-37, 2005 Mar 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15753368
18.
Computational design of TNF ligand-based protein therapeutics.
Adv Exp Med Biol;
691: 521-34, 2011.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21153357
19.
Stabilization of TRAIL, an all-beta-sheet multimeric protein, using computational redesign.
Protein Eng Des Sel;
17(9): 673-80, 2004 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15486023
20.
Binding of phage displayed Bacillus subtilis lipase A to a phosphonate suicide inhibitor.
J Biotechnol;
101(1): 19-28, 2003 Feb 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12523966