Population-based seroprevalence of SARS-CoV-2 and the herd immunity threshold in Maranhão
Rev. saúde pública (Online)
; 54: 131, 2020. tab, graf
Article
em En
| LILACS, BBO, SES-SP
| ID: biblio-1145072
Biblioteca responsável:
BR1.1
ABSTRACT
ABSTRACT OBJECTIVE:
To estimate the seroprevalence of SARS-CoV-2 in the state of Maranhão, Brazil.METHODS:
A population-based household survey was performed, from July 27, 2020 to August 8, 2020. The estimates considered clustering, stratification and non-response. Qualitative detection of IgM and IgG antibodies was performed in a fully-automated Elecsys® Anti-SARS-CoV-2 electrochemiluminescence immunoassay on the Cobas® e601 analyzer (Roche Diagnostics).RESULTS:
In total, 3,156 individuals were interviewed. Seroprevalence of total antibodies against SARS-CoV-2 was 40.4% (95%CI 35.6-45.3). Population adherence to non-pharmaceutical interventions was higher at the beginning of the pandemic than in the last month. SARS-CoV-2 infection rates were significantly lower among mask wearers and among those who maintained social and physical distancing in the last month compared to their counterparts. Among the infected, 26.0% were asymptomatic. The infection fatality rate (IFR) was 0.14%, higher for men and older adults. The IFR based on excess deaths was 0.28%. The ratio of estimated infections to reported cases was 22.2.CONCLUSIONS:
To the best of our knowledge, the seroprevalence of SARS-CoV-2 estimated in this population-based survey is one of the highest reported. The local herd immunity threshold may have been reached or might be reached soon.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
BBO
/
LILACS
/
SES-SP
Assunto principal:
Estudos Soroepidemiológicos
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Imunidade Coletiva
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COVID-19
/
Anticorpos Antivirais
Tipo de estudo:
Qualitative_research
Limite:
Adolescent
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Adult
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Aged
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Child
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Child, preschool
/
Female
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Humans
/
Infant
/
Male
/
Newborn
País/Região como assunto:
America do sul
/
Brasil
Idioma:
En
Revista:
Rev. saúde pública (Online)
Assunto da revista:
Sa£de P£blica
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
Brasil