Primary pulmonary hypertension is not associated with scleroderma-like changes in nailfold capillaries.
Chest
; 120(3): 796-800, 2001 Sep.
Article
em En
| MEDLINE
| ID: mdl-11555512
ABSTRACT
STUDY OBJECTIVES:
To determine whether primary pulmonary hypertension (PPH) is associated with scleroderma-like changes in nailfold capillaries.DESIGN:
Blinded, prospective, case-control study.SETTING:
University medical centers in Baltimore, MD. PATIENTS Thirty-seven patients with PPH, 15 patients with scleroderma, and 13 healthy control subjects. MEASUREMENTS Subjects underwent nailfold capillary videomicroscopy of the fourth digits of both hands. Capillary images were evaluated by two blinded, trained graders according to standardized criteria for the presence of scleroderma nailfold changes.RESULTS:
The prevalence of scleroderma-associated nailfold changes in patients with PPH (1 of 37 patients) was dramatically lower than that in patients with scleroderma (9 of 15 patients; p < 0.0001). The distribution of nailfold grades for the PPH patients was indistinguishable from that of the healthy control subjects.CONCLUSION:
PPH is not associated with scleroderma-like vasculopathy of nailfold capillaries.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Escleroderma Sistêmico
/
Hipertensão Pulmonar
/
Unhas
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Chest
Ano de publicação:
2001
Tipo de documento:
Article
País de afiliação:
Estados Unidos