Lifestyle, family history and progression of hypertension.
J Hypertens
; 24(8): 1479-87, 2006 Aug.
Article
em En
| MEDLINE
| ID: mdl-16877948
ABSTRACT
BACKGROUND:
Unhealthy lifestyle practices are risk factors for future hypertension.OBJECTIVES:
The aim of this study was to investigate the association between lifestyle changes over a 6-year period and the risk of developing sustained hypertension in a cohort of young hypertensive individuals, and to identify the predictors of lifestyle impairment over time.METHODS:
Seven-hundred and eighty never-treated hypertensive HARVEST participants, 18-45 years old, were studied.RESULTS:
Only modest mean behavioral changes were observed during follow-up. This, however, was the net result of many participants improving and others worsening their lifestyle. Participants with a family history of hypertension (FH+, n = 459) had more undesirable lifestyles (P = 0.004) and higher clinic and ambulatory blood pressures (P = 0.03) at baseline than participants without a family history of hypertension (FH-). During the 6-year follow-up, FH- individuals strikingly worsened their lifestyle while FH+ participants exhibited impressive improvements (P < 0.00001). Other predictors of lifestyle impairment were male gender (P = 0.003) and age (P = 0.02). Adoption of an unfavorable lifestyle was accompanied by an increased risk of developing sustained hypertension (P = 0.04). Initiation of drug therapy for hypertension was significantly higher among FH- than FH+ individuals (53 versus 45%, respectively; P = 0.045).CONCLUSIONS:
'Lower risk' FH- stage 1 hypertensive individuals may initially be at higher risk of developing more severe hypertension in comparison with their FH+ counterparts. This increased risk may be attributed to worsening of their lifestyle profiles over time. Healthy lifestyles should be emphasized to all hypertensive individuals including patients with favorable lifestyle profiles.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Família
/
Hipertensão
/
Estilo de Vida
Tipo de estudo:
Clinical_trials
/
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
/
Middle aged
País/Região como assunto:
Europa
Idioma:
En
Revista:
J Hypertens
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
Itália