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Synthesis of α-carboranyl-α-acyloxy-amides as potential BNCT agents.
Jonnalagadda, Subash C; Cruz, Jonathan S; Connell, Ryan J; Scott, Patricia M; Mereddy, Venkatram R.
Afiliação
  • Jonnalagadda SC; Department of Chemistry and Biochemistry, Rowan University, Glassboro, NJ 08051.
Tetrahedron Lett ; 50(30): 4314-4317, 2009 Jul 29.
Article em En | MEDLINE | ID: mdl-20160970
Novel α-carboranyl-α-acyloxy-amides were prepared as potential BNCT agents utilizing three component Passerini reaction. Preliminary cytotoxicity of the representative compounds on two brain tumor cell lines (U-87 and A-172) showed no effect on cell viability; an essential requirement for utility as potential BNCT agents.

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Tetrahedron Lett Ano de publicação: 2009 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Tetrahedron Lett Ano de publicação: 2009 Tipo de documento: Article