Suppression of melatonin secretion in healthy subjects with eyeglass LED delivery system.
Neuro Endocrinol Lett
; 31(3): 330-5, 2010.
Article
em En
| MEDLINE
| ID: mdl-20588229
ABSTRACT
OBJECTIVE:
Practicability remains a problem in light therapy of biological rhythm disorders. We report here the effect on melatonin secretion of a device consisting of a prototype of eyeglasses including light emitting diodes (LED) in lenses (Somnavue).METHODS:
Light (1,200 lx) was administered in a randomised crossover design to ten healthy subjects with Somnavue for 1 or 2 hours, Lumino (a helmet which administers light) for 1 hour, and placebo, beginning at 0100 h. Plasma melatonin concentrations were evaluated between 2000-0500 h.RESULTS:
Multiple comparisons showed differences between placebo and Somnavue administered for one or two hours (p<0.01 and p<0.05 respectively) and Lumino and placebo (p<0.05).CONCLUSIONS:
In conclusion, Somnavue was able to suppress melatonin. The development of such a device could increase adherence with light treatment in SAD or circadian rhythm sleep disorders.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Estimulação Luminosa
/
Melatonina
Tipo de estudo:
Clinical_trials
Limite:
Adolescent
/
Adult
/
Humans
Idioma:
En
Revista:
Neuro Endocrinol Lett
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
França